一般描述
Angiotensin-converting enzyme (ACE) is a zinc-metallopeptidase belonging to the peptidase M2 family. It catalyzes the conversion of angiotensin I to angiotensin II and the degradation of bradykinin, which increases the vasoconstrictive effects of angiotensin. The Angiotensin-converting enzyme plays an important role in maintaining cardiac function and vascular tone. It is highly expressed in the heart, lung, kidney, gastrointestinal system, and prostate. Defects in the Angiotensin-converting may contribute cardiac disease; and renal tubular dysgenesis, a condition characterized by persistent fetal anuria and perinatal death.
~180 kDa observed. The calculated molecular weight is 150 kDa; however, this protein is known to be glycolsylated.
免疫原
Human Angiotensin Converting Enzyme.
应用
Anti-Angiotensin Converting Enzyme Antibody, clone 2E2.
联系
Replaces: MAB3502
外形
Mouse monoclonal IgG1 cultured supernatant without preservatives.
分析说明
Control
Rat Angiotensin Converting Enzyme
Rat Angiotensin Converting Enzyme
Evaluated by Western Blot in rat Angiotensin Converting Enzyme.
Western Blot Analysis: A 1:2,000 dilution of this antibody detected rat Angiotensin Converting Enzyme in WB.
Western Blot Analysis: A 1:2,000 dilution of this antibody detected rat Angiotensin Converting Enzyme in WB.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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