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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
monoclonal
Species reactivity:
mouse, human
Application:
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Technique(s):
ELISA: suitable
immunocytochemistry: suitable
western blot: suitable
immunocytochemistry: suitable
western blot: suitable
Citations:
5
Uniprot accession no.:
产品名称
抗-PPAR γ1和2抗体,磷酸特异性(Ser112), ascites fluid, Chemicon®
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
monoclonal
species reactivity
mouse, human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunocytochemistry: suitable
western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
phosphorylation (pSer112)
Quality Level
Gene Information
human ... PPARG(5468)
Application
使用经ELISA、WB、ICC验证的抗PPARγ1 & 2抗体,磷酸特异性(Ser112)(小鼠单克隆抗体)检测PPARγ1 & 2(也称为过氧化物酶体增殖物激活受体γ 1 & 2)。
研究子类别
转录因子
转录因子
研究类别
表观遗传学&核功能
表观遗传学&核功能
蛋白质印迹:内源和重组蛋白上为1:500-1:5,000。
免疫细胞化学:1:500-1:5000
ELISA:1:500-1:5000
最佳工作稀释度必须由最终用户确定。
免疫细胞化学:1:500-1:5000
ELISA:1:500-1:5000
最佳工作稀释度必须由最终用户确定。
Biochem/physiol Actions
识别磷酸化过氧化物酶体增殖物激活受体(PPAR)γ1和γ2。
Disclaimer
除非我们的目录或产品随附的其他公司文件中另有说明,否则我们的产品预期仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
Immunogen
来自人PPARγ2(与PPARγ1相同)氨基酸107-121的磷酸化(丝氨酸112)合成肽。 与PPARα或PPARβ无同源性。
表位:磷酸特异性(Ser112)
Physical form
腹水。 液体。 不含防腐剂。
Preparation Note
接收后,以未稀释的等分试样在-20°C下保存长达6个月。 应避免反复冻/融循环。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling.
Tobias B Huber et al.
Molecular and cellular biology, 23(14), 4917-4928 (2003-07-02)
Mutations of NPHS1 or NPHS2, the genes encoding nephrin and podocin, as well as the targeted disruption of CD2-associated protein (CD2AP), lead to heavy proteinuria, suggesting that all three proteins are essential for the integrity of glomerular podocytes, the visceral
Larry A Denner et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(47), 16725-35a-16725-35a (2012-11-24)
We previously reported that the peroxisome proliferator-activated receptor γ (PPARγ) agonist rosiglitazone (RSG) improved hippocampus-dependent cognition in the Alzheimer's disease (AD) mouse model, Tg2576. RSG had no effect on wild-type littermate cognitive performance. Since extracellular signal-regulated protein kinase mitogen-activated protein
Dalila El Ouarrat et al.
Cell metabolism, 31(1), 162-173 (2019-11-12)
Insulin resistance is a major factor in obesity-linked type 2 diabetes. PPARγ is a master regulator of adipogenesis, and small molecule agonists, termed thiazolidinediones, are potent therapeutic insulin sensitizers. Here, we studied the role of transcriptional co-activator with PDZ-binding motif
Bo-Mi Kim et al.
International journal of molecular medicine, 43(1), 489-500 (2018-10-27)
Muscat Bailey A grape stalk is an organic waste produced in marked amounts during the vinification of grapes. Previous studies have indicated that grape stalk is rich in bioactive phenolic compounds, and exhibits antioxidant and UV‑protective activities. However, its effects
Keisuke Yanagida et al.
JCI insight, 3(24) (2018-12-21)
White adipose tissue (WAT) can dynamically expand and remodel through adipocyte hypertrophy and hyperplasia. The relative contribution of these 2 mechanisms to WAT expansion is a critical determinant of WAT function and dysfunction in obesity. However, little is known about
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