Mouse Anti-Human Maspin, clone 3B8.2 (1mg) KC

FUNCTION: SwissProt: P36952 # Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
SIZE: 375 amino acids; 42138 Da
SUBCELLULAR LOCATION: Secreted, extracellular space.
TISSUE SPECIFICITY: Normal mammary epithelial cells.
SIMILARITY: SwissProt: P36952 ## Belongs to the serpin family. Ov-serpin subfamily.

Synthetic peptide corresponding to amino acids 112-130 of human Maspin. The immunogen sequence is 100% identical in mouse.

Western blot (1:10,000)

Optimal working dilutions must be determined by end user.

Recognizes human Maspin. Maspin functions as a tumor suppressor, blocking the growth, invasion, and metastatic properties of mammary tumors. This antibody detects an ~42 kDa band, corresponding to the expected molecular weight of Maspin.

Protein A purified immunoglobulin. Liquid in 0.02 M Phosphate with 0.15 M NaCl, pH 7.6 and 0.1% sodium azide as a preservative.

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

This product is intended for use by IVD manufacturers.
Contact customer service for assistance: oem.reagents@emdmillipore.com

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