biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
clone
ST126, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
neutralization: suitable
isotype
IgG2b
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Immunogen
Human alpha-interferon
Application
Anti-Interferon-α Antibody, clone ST126 detects level of Interferon-α & has been published & validated for use in NEUT.
Neutralizes anti-viral activity of interferon.
Dilute with buffer pH 7.5 - 8.0 to desired working volumes. Final working dilutions must be determined by end user. For extensive dilution use protein-containing or other stabilizing medium.
Dilute with buffer pH 7.5 - 8.0 to desired working volumes. Final working dilutions must be determined by end user. For extensive dilution use protein-containing or other stabilizing medium.
Research Category
Inflammation & Immunology
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
Cytokines & Cytokine Receptors
Biochem/physiol Actions
Human interferon-alpha sub-species. Distinguishes between sub-species of human alpha-interferon. Can be used to detect interferon oligomers.
Physical form
Liquid, no preservatives.
Preparation Note
Maintain at -20°C for up to 12 months.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Monoclonal antibodies that distinguish between subspecies of human interferon-alpha and that detect interferon oligomers.
Shearer, M, et al.
Journal of immunology (Baltimore, Md. : 1950), 133, 3096-3101 (1984)
Marlena M Westcott et al.
Journal of virology, 89(15), 7944-7954 (2015-05-23)
Oncolytic viruses (OV) preferentially kill cancer cells due in part to defects in their antiviral responses upon exposure to type I interferons (IFNs). However, IFN responsiveness of some tumor cells confers resistance to OV treatment. The human type I IFNs
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