跳转至内容
Merck
CN

MAB4162

抗-MDR1抗体，细胞外人类特异性Pgp，克隆号MM4.17

clone MM4.17, Chemicon®, from mouse

别名:

P-glycoprotein, CD243, p170, Pgp

登录 查看组织和合同定价。

选择尺寸

关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
MM4.17, monoclonal
Species reactivity:
human
Application:
flow cytometry
immunohistochemistry
Technique(s):
flow cytometry: suitable
immunohistochemistry: suitable
Citations:
5
Uniprot accession no.:
P08183

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

抗-MDR1抗体，细胞外人类特异性Pgp，克隆号MM4.17, clone MM4.17, Chemicon®, from mouse

biological source

mouse

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

MM4.17, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

flow cytometry: suitable
immunohistochemistry: suitable

isotype

IgG2aκ

NCBI accession no.

NM_000927.3

UniProt accession no.

P08183

shipped in

wet ice

Quality Level

300

相关类别

Biochem/physiol Actions

识别细胞外Pgp结构域的一个表位，并在活（完整）人类MDR细胞中检测低水平的Pgp表达（Cianfriglia，2002）。 使用不同的技术将表位定位到单氨基酸水平（Cianfriglia，1994和Poloni，1995）。

Other Notes

浓度：请参考批次特异性浓缩物的检验报告。

Physical form

形式：纯化

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Application

流式细胞术

丙酮固定石蜡包埋切片的免疫组化

共聚焦和电子显微镜

ELISA

最佳工作稀释度必须由最终用户进行确定。
抗-MDR1抗体，细胞外人类特异性Pgp，克隆号MM4.17是一种抗MDR1抗体，用于FC、IH。

未找到合适的产品？  

试试我们的产品选型工具.

存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Paola Turella et al.
The Journal of biological chemistry, 281(33), 23725-23732 (2006-06-14)
The new glutathione S-transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) is cytotoxic toward P-glycoprotein-overexpressing tumor cell lines, i.e. CEM-VBL10, CEM-VBL100, and U-2 OS/DX580. The mechanism of cell death triggered by NBDHEX has been deeply investigated in leukemia cell lines. Kinetic data indicate a
Marine Chartrain et al.
PloS one, 7(5), e36762-e36762 (2012-06-08)
Metastatic melanoma is the most aggressive skin cancer. Recently, phenotypically distinct subpopulations of tumor cells were identified. Among them, ABCB5-expressing cells were proposed to display an enhanced tumorigenicity with stem cell-like properties. In addition, ABCB5(+) cells are thought to participate
Masahiro Yasunaga et al.
Scientific reports, 4, 4852-4852 (2014-05-02)
The treatment of colorectal cancer (CRC) might be improved by the identification of a signalling pathway that could be targeted with novel therapeutics. The results of this study indicate that the taurine transporter SLC6A6 is highly expressed in CRC cells
Jingwei Zhang et al.
British journal of pharmacology, 165(1), 120-134 (2011-05-28)
Intracellular pharmacokinetics of anticancer drugs in multi-drug resistance (MDR) cancer cells is hugely important in the evaluation and improvement of drug efficacy. By using adriamycin as a probe drug in MDR cancer cells, we developed a cellular pharmacokinetic-pharmacodynamic (PK-PD) model
Wanyuan Chen et al.
Oncology reports, 41(1), 67-76 (2018-10-27)
Pancreatic cancer (PC) is a lethal solid malignancy with resistance to traditional chemotherapy. Recently, considerable studies have demonstrated the ubiquitous antitumor properties of gene therapy mediated by the oncolytic vaccinia virus. The second mitochondrial‑derived activator of caspase (Smac) has been

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持