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Merck
CN

MAB4350

Sigma-Aldrich

Anti-BMP-7 Antibody, clone 2A10

clone 2A10, from mouse

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41
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生物来源

mouse

质量水平

偶联物

unconjugated

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

2A10, monoclonal

种属反应性

mouse, human

技术

immunohistochemistry: suitable
western blot: suitable

输入

sample type mesenchymal stem cell(s)

同位素/亚型

IgG1κ

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... BMP7(655)
mouse ... Bmp7(12162)

一般描述

46 kDa
Bone morphogenetic protein-7 (BMP-7), also known as osteogenic protein-1, is a member of the TGF- superfamily, and is widely expressed during embryonic development. Like other members of the bone morphogenetic protein family, BMP-7 works synergistically with BMP-2 to play a key role in the differentiation of mesenchymal cells into bone and cartilage tissues by actively recruiting stem cells from the surrounding tissue, thereby initiating the bone formation cascade. In adult cells, BMP-7 is predominately expressed in the brain, kidneys, and bladder.

应用

Immunohistochemistry: Recommended working dilution is 1:50.

Western Blotting: Recommended working concentration is 1 – 2 µg/mL.
This Anti-BMP-7 Antibody, clone 2A10 is validated for use in WB, IH for the detection of BMP-7.

生化/生理作用

Reactivity with other species has not been tested.

外形

Format: Purified
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4),
150 mM NaCl, and 0.05% sodium azide.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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