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Merck
CN

MAB4388

小鼠抗-Stella 抗体

clone 3H5.2, Chemicon®, from mouse

别名:

Anti-Anti-Pgc7, Anti-Anti-STELLA

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
3H5.2, monoclonal
Application:
ELISA
immunocytochemistry
Species reactivity:
mouse, human
Citations:
13
Technique(s):
ELISA: suitable
immunocytochemistry: suitable
Uniprot accession no.:
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产品名称

小鼠抗-Stella 抗体, clone 3H5.2, Chemicon®, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

3H5.2, monoclonal

species reactivity

mouse, human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunocytochemistry: suitable

input

sample type: human embryonic stem cell(s)
sample type induced pluripotent stem cell(s)
sample type: mouse embryonic stem cell(s)

isotype

IgG1

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

mouse ... Dppa3(73708)

Application

抗-Stella抗体可检测Stella的水平&已有相关文献发表& 经验证可用于 ELISA & IC。
研究子类别
多能&早期分化
研究类别
干细胞研究

Biochem/physiol Actions

与人和小鼠的stella 反应。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

General description

Stella 是在原肠胚出现时由卵母细胞、多能细胞和原始生殖细胞特异性表达的,是小鼠胚胎裂解期的重要母体因子(Bortvin, 2004)。尽管stella在生殖细胞中特异性分化的要求仍然存有争议,但是,来自stella 缺乏小鼠的大多数胚胎无法正常发育,并很少达到囊胚期(Bortvin, 2004; Payer, 2003)。 stella 基因编码一种带有类SAP 结构域和剪接因子基序样(splicing factor motif-like)结构的蛋白,表明其在染色体组织结构和RNA 加工中的可能作用(Payer, 2003)。

Other Notes

浓度:请参考批次特异性浓缩物的检验报告。

Physical form

形式:纯化
溶于含0.1%叠氮化钠的PBS中的纯化免疫球蛋白液体。

Preparation Note

以未稀释的等分形式可在2-8C冷藏保存长达12个月。

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Katja Linher et al.
PloS one, 4(12), e8263-e8263 (2009-12-17)
We have previously demonstrated that stem cells isolated from fetal porcine skin have the potential to form oocyte-like cells (OLCs) in vitro. However, primordial germ cells (PGCs), which must also be specified during the stem cell differentiation to give rise
Human primordial germ cell commitment in vitro associates with a unique PRDM14 expression profile.
Sugawa, F; Arauzo-Bravo, MJ; Yoon, J; Kim, KP; Aramaki, S; Wu, G; Stehling, M; Psathaki et al.
The Embo Journal null
Pengxiang Wang et al.
Cell proliferation, 57(1), e13533-e13533 (2023-08-04)
Primordial germ cells (PGCs) are the germline precursors that give rise to oocytes and sperm, ensuring the continuation of life. While the PGC specification is extensively studied, it remains elusive how the PGC population is sustained and expanded after they
Xun Xu et al.
Nature materials (2024-08-13)
Naive pluripotent stem cells have the highest developmental potential but their in vivo existence in the blastocyst is transient. Here we report a blastocyst motif substrate for the in vitro reversion of mouse and human pluripotent stem cells to a
Maurizio Zuccotti et al.
BMC developmental biology, 8, 97-97 (2008-10-08)
The maternal contribution of transcripts and proteins supplied to the zygote is crucial for the progression from a gametic to an embryonic control of preimplantation development. Here we compared the transcriptional profiles of two types of mouse MII oocytes, one

相关内容

As the focus of stem cell research undergoes a transition from animal to human models, researchers are in critical need of validated products to support the isolation, maintenance, differentiation, and characterization of human stem cells. While many reagents designed for rodent systems can be applied to human stem cell studies, they are not truly optimized for robust human stem cell culture or analysis. This is why human stem cell researchers have always trusted EMD Millipore, the first provider of commercially available human embryonic stem cells and human neural stem cell lines, to accelerate their research. All of our human stem cell systems are extensively tested in defined media culture, and differentiated progeny are comprehensively characterized with highly validated antibodies and detection reagents.

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