MAB5456
Anti-Gonadotropin-Releasing Hormone Antibody, NT, clone HU11B
ascites fluid, clone HU11B, Chemicon®
别名:
GnRH, Luteinizing Hormone-Releasing Hormone, LHRH
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
HU11B, monoclonal
species reactivity
hamster, shrimp, mouse, monkey, rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable (paraffin)
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
mouse ... Gnrh1(14714)
Immunogen
Epitope: N-terminus
Mouse GnRH (QHWSYGLRPG) conjugated to bovine thyroglobulin.
Application
Immunohistochemistry on 4% paraformaldehyde fixed tissue sections.
Immunocytochemistry
Optimal working dilutions must be determined by end user.
Immunocytochemistry
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Hormones & Receptors
Hormones & Receptors
This Anti-Gonadotropin-Releasing Hormone Antibody, N-terminus, clone HU11B is validated for use in IH(P) for the detection of Gonadotropin-Releasing Hormone.
Biochem/physiol Actions
Reacts with mammalian Gonadotropin-releasing hormone.
Physical form
Ascites fluid. Liquid. Contains no preservative.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Santiago E Charif et al.
Physiological reports, 5(19) (2017-10-19)
Females of the South American plains vizcacha, Lagostomus maximus, show peculiar reproductive features such as massive polyovulation up to 800 oocytes per estrous cycle and an ovulatory process around mid-gestation arising from the reactivation of the hypothalamic-hypophyseal-ovary (H.H.O.) axis. Estradiol
Aleisha M Moore et al.
Scientific reports, 8(1), 2242-2242 (2018-02-06)
Kisspeptin/Neurokinin B/Dynorphin (KNDy) neurons of the arcuate nucleus (ARC) play a key role in the regulation of fertility. The ability to detect features of KNDy neurons that are essential for fertility may require three-dimensional (3D) imaging of the complete population.
S E Rietema et al.
Reproduction, fertility, and development, 31(11), 1682-1691 (2019-09-13)
Rams respond to acute nutritional supplementation by increasing the frequency of gonadotrophin-releasing hormone (GnRH) pulses. Kisspeptin neurons may mediate the effect of environmental cues on GnRH secretion, so we tested whether the ram response to nutrition involves activation of kisspeptin
Diana E Peragine et al.
Proceedings of the National Academy of Sciences of the United States of America, 114(5), 1207-1212 (2017-01-18)
Neuroendocrine mechanisms underlying social inhibition of puberty are not well understood. Here, we use a model exhibiting the most profound case of pubertal suppression among mammals to explore a role for RFamide-related peptide-3 [RFRP-3; mammalian ortholog to gonadotropin-inhibitory hormone (GnIH)]
Yang Li et al.
PloS one, 17(6), e0259609-e0259609 (2022-06-16)
Polycystic ovary syndrome often starts in puberty, and its pathogenesis is not clear. This study aimed to explore the pathogenesis of pubertal polycystic ovary syndrome (PCOS) and assess the therapeutic effect of electroacupuncture on pubertal PCOS. Dihydrotestosterone (DHT) was used
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