产品名称
Anti-Serotonin Transporter Antibody, ascites fluid, Chemicon®
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
monoclonal
species reactivity
primate, human
should not react with
rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... HTT(3064), SLC6A4(6532)
Application
Anti-Serotonin Transporter Antibody detects level of Serotonin Transporter & has been published & validated for use in IH.
Immunohistochemistry: 1:500-1:1,000 on 10% formalin fixed, paraffin embedded tissue from human Medulla oblongata. Suggested antigen retrieval method is Heat Induced Epitope Retrieval (HIER): Citrate Buffer pH 6.0.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Ion Channels & Transporters
Biochem/physiol Actions
Serotonin Transporter, human and non-human primate.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Synthetic peptide from human serotonin transporter.
Physical form
Ascites
Preparation Note
Maintain at -20degC in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Smriti Patodia et al.
Brain pathology (Zurich, Switzerland), 32(5), e13074-e13074 (2022-04-29)
Several lines of evidence link deficient serotonin function and SUDEP. Chronic treatment with serotonin reuptake inhibitors (SRIs) reduces ictal central apnoea, a risk factor for SUDEP. Reduced medullary serotonergic neurones, modulators of respiration in response to hypercapnia, were reported in
Anke J Borgers et al.
Frontiers in neuroscience, 8, 106-106 (2014-05-27)
That serotonin plays a role in the regulation of feeding behavior and energy metabolism has been known for a long time. Serotonin transporters (SERT) play a crucial role in serotonin signaling by regulating its availability in the synaptic cleft. The
Jonas Woll Jørandli et al.
American journal of physiology. Gastrointestinal and liver physiology, 319(6), G761-G768 (2020-09-25)
Serotonin is a highly conserved and ubiquitous signaling molecule involved in a vast variety of biological processes. A majority of serotonin is produced in the gastrointestinal epithelium, where it is suggested to act as a prominent regulatory molecule in the
Caroline H Lew et al.
American journal of physical anthropology, 170(3), 351-360 (2019-07-02)
The serotonergic system is involved in the regulation of socio-emotional behavior and heavily innervates the amygdala, a key structure of social brain circuitry. We quantified serotonergic axon density of the four major nuclei of the amygdala in humans, and examined
Danielle N Jones et al.
The Journal of comparative neurology, 529(7), 1659-1668 (2020-10-07)
The genus Macaca is an ideal model for investigating the biological basis of primate social behavior from an evolutionary perspective. A significant amount of behavioral diversity has been reported among the macaque species, but little is known about the neural
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