产品名称
Anti-Plectin Antibody, Clone 10F6, clone 10F6, Chemicon®, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
10F6, monoclonal
species reactivity
mouse, human, rat
manufacturer/tradename
Chemicon®
technique(s)
immunohistochemistry: suitable
western blot: suitable
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Analysis Note
Control
rat brain tissue lysate
rat brain tissue lysate
Routinely tested on rat brain tissue lysate
Application
Detect Plectin using this Anti-Plectin Antibody, Clone 10F6 validated for use in WB, IH.
Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neuronal & Glial Markers
Neurodegenerative Diseases
Neuronal & Glial Markers
Biochem/physiol Actions
Cat. # MAB5674 recognizes the cytoplasmic domain of Plectin.
Reactivity with other species has not been tested.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
General description
300-500 kDa
The product of this gene belongs to the plakin or cytolinker family of genes. The encoded protein is involved in cytoskeleton-membrane attachment in epithelial cells, muscle, and other tissues. It also may regulate changes of lymphocyte cytoarchitecture during polarization and extravasation. This gene has alternative splicing of different 5′ exons to the first constant exon, which generates transcript variants that encode distinct isoforms
Immunogen
Gel-purified C5 Cell plectin
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Format: Purified
Purified in PBS with 0.05% NaN3
Preparation Note
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Elena Ambrosini et al.
Glia, 41(3), 290-300 (2003-01-16)
Macrophage inflammatory protein-3alpha/CCL20 is a recently identified chemokine that binds to CCR6 and acts as a chemoattractant for memory/differentiated T-cells, B-cells, and immature dendritic cells. We have previously reported that CCL20 and CCR6 mRNAs are expressed in the CNS of
Sarah D Ackerman et al.
The Journal of experimental medicine, 215(3), 941-961 (2018-01-26)
Myelin is a multilamellar sheath generated by specialized glia called Schwann cells (SCs) in the peripheral nervous system (PNS), which serves to protect and insulate axons for rapid neuronal signaling. In zebrafish and rodent models, we identify GPR56/ADGRG1 as a
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