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MAB7774

Sigma-Aldrich

Anti-Urokinase Antibody, NT fragment, clone 10D.7.2

clone 10D.7.2, Chemicon®, from mouse

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别名:
uPA
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

10D.7.2, monoclonal

种属反应性

human

制造商/商品名称

Chemicon®

技术

ELISA: suitable
western blot: suitable

同位素/亚型

IgG2a

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... PLAU(5328)

特异性

Urokinase Plasminogen Acitivator is a serine protease (SERPIN) that converts plasminogen into the active protease plasmin. uPA is secreted from cells in as the inactive 52 kDa single chain precursor which is activated into the two chain form consisting of an alpha and beta chain.MAB7774 is specific for Human uPA, other species not tested.

免疫原

Amino Terminal Fragment of uPA
Epitope: N-terminus fragment

应用

Research Category
Metabolism
Research Sub Category
Enzymes & Biochemistry
This Anti-Urokinase Antibody, N-terminus fragment, clone 10D.7.2 is validated for use in ELISA, WB for the detection of Urokinase.
Western blot: 1:1000-1:3000

ELISA

Optimal working dilutions must be determined by end user.

联系

Replaces: AB776

外形

Format: Purified
Purified immunoglobulin. Liquid in 0.02 M phosphate buffer containing 0.25 M NaCl2 and 0.1% NaN3.

储存及稳定性

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 6 months.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Falgun Shah et al.
Cell chemical biology, 24(7), 858-869 (2017-07-04)
Cutaneous reactions represent one of the most common adverse drug effects observed in clinical trials leading to substantial compound attrition. Three negative allosteric modulators (NAMs) of metabotropic glutamate receptors (mGluRs), which represent an important target for neurological diseases, developed by

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