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Merck
CN

MAB8292

Anti-Parvovirus B19 Antibody, clone 521-5D

clone 521-5D, Chemicon®, from mouse

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
521-5D, monoclonal
Species reactivity:
human
Application:
ELISA, ICC, IHC (p)
Citations:
19
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biological source

mouse

antibody form

purified immunoglobulin

clone

521-5D, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable, immunocytochemistry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable

isotype

IgG

shipped in

wet ice

Quality Level

Immunogen

B-19 virus purified from an acute serum specimen from a child with aplastic crisis (Anderson, 1986).

Application

Immunoassay.

Immunocytochemistry

Optimal working dilutions must be determined by end user.
Research Category
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
This Anti-Parvovirus B19 Antibody, clone 521-5D is validated for use in ELISA, IC, IH, IH(P) for the detection of Parvovirus B19.

Biochem/physiol Actions

Human parvovirus B19. Recognizes amino acids 446-466 of VP2. Antibody inhibits haemagglutination.

Physical form

Format: Purified
Purified immunoglobulin. In 0.02M PB and 0.25M NaCl pH=7.6 with 0.1% NaN3 as a preservative.

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 12 months

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Recombinant parvovirus B19 empty capsids inhibit fetal hematopoietic colony formation in vitro.
B Lindton, T Tolfvenstam, O Norbeck, L Markling, O Ringden, M Westgren, K Broliden
Fetal Diagnosis and Therapy null
Peng Xu et al.
Antimicrobial agents and chemotherapy, 63(3) (2018-12-12)
Human parvovirus B19 (B19V), a member of the genus Erythroparvovirus of the family Parvoviridae, is a small nonenveloped virus that has a single-stranded DNA (ssDNA) genome of 5.6 kb with two inverted terminal repeats (ITRs). B19V infection often results in
Laura A Adamson et al.
Journal of medical virology, 86(9), 1614-1620 (2013-11-23)
Human erythrovirus B19 (EVB19) is a small, pathogenic DNA virus that has been associated with a wide range of illnesses. The primary site of replication is in bone marrow-derived erythroid progenitor cells, but EVB19 DNA has been detected in a
Placental cellular immune response in women infected with human parvovirus B19 during pregnancy.
Jordan, JA; Huff, D; DeLoia, JA
Clinical and Diagnostic Laboratory Immunology null
Human parvovirus B19 infection in acute fulminant liver failure.
Y V Karetnyi, P R Beck, R S Markin, A N Langnas, S J Naides
Archives of Virology null

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