生物来源
mouse
质量水平
抗体形式
purified immunoglobulin
克隆
1B7, monoclonal
种属反应性
human
制造商/商品名称
Chemicon®
技术
ELISA: suitable
immunofluorescence: suitable
同位素/亚型
IgG2a
运输
wet ice
免疫原
Epitope: localized to the M1 protein human metapneumovirus
MPV CAN98-75
应用
Detect Human Metapneumovirus 75.1 using this Anti-Human Metapneumovirus 75.1 Antibody, clone 1B7 validated for use in ELISA & IF.
ELISA
Immunofluorescence:
It is difficult to grow the metapneumovirus in standard cell lines. LLC-MK2 can be used for culture; acetone fixation is recommended. See Ebihara, 2005.
Optimal dilutions must be determined by the end user
Immunofluorescence:
It is difficult to grow the metapneumovirus in standard cell lines. LLC-MK2 can be used for culture; acetone fixation is recommended. See Ebihara, 2005.
Optimal dilutions must be determined by the end user
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
生化/生理作用
Recognizes Human Metapneumoviruses. Reacts against both A and B antigenic groups and subgroups 1 and 2.
外形
Protein A purified
Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.
制备说明
Maintain for 1 year at 2–8°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
分析说明
Control
Metapneumovirus positive patient sample
Metapneumovirus positive patient sample
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Akitaka Fujita et al.
Frontiers in immunology, 11, 432-432 (2020-03-29)
Viral infections of the airway can exacerbate respiratory diseases, such as asthma or chronic obstructive pulmonary disease (COPD), and accelerate disease progression. Phosphoinositide 3-kinase (PI3K)δ, a class 1A PI3K, has been studied as a potential target for achieving anti-oncogenic and
Detection of respiratory viruses by molecular methods.
Mahony, JB
Clinical Microbiology Reviews null
Marlies Ballegeer et al.
mBio, 15(1), e0212223-e0212223 (2023-12-20)
Human metapneumovirus (hMPV) is an important respiratory pathogen for which no licensed antivirals or vaccines exist. Single-domain antibodies represent promising antiviral biologics that can be easily produced and formatted. We describe the isolation and detailed characterization of two hMPV-neutralizing single-domain
Tomohiro Ogawa et al.
Frontiers in immunology, 12, 767666-767666 (2021-12-14)
Bronchial epithelial cells are front sentinels eliciting innate and adaptive immunity to respiratory viral pathogens. Recognition of viral double-stranded RNA induces antiviral interferon (IFN) responses in bronchial epithelial cells. Co-inhibitory molecules programmed cell death 1 ligand 1 (PD-L1) and ligand
Antonella Bugatti et al.
Microorganisms, 8(6) (2020-06-04)
Human Metapneumovirus (HMPV) is a major cause of lower respiratory tract infections. HMPV infection has been hypothesized to alter dendritic cell (DC) immune response; however, many questions regarding HMPV pathogenesis within the infected lung remain unanswered. Here, we show that
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