MAB8510
Anti-Human Metapneumovirus 75.1 Antibody, clone 1B7
clone 1B7, Chemicon®, from mouse
别名:
Metapneumovirus
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
1B7, monoclonal
Species reactivity:
human
Application:
ELISA, IF
Citations:
10
biological source
mouse
antibody form
purified immunoglobulin
clone
1B7, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunofluorescence: suitable
isotype
IgG2a
shipped in
wet ice
Quality Level
Immunogen
Epitope: localized to the M1 protein human metapneumovirus
MPV CAN98-75
Application
Detect Human Metapneumovirus 75.1 using this Anti-Human Metapneumovirus 75.1 Antibody, clone 1B7 validated for use in ELISA & IF.
ELISA
Immunofluorescence:
It is difficult to grow the metapneumovirus in standard cell lines. LLC-MK2 can be used for culture; acetone fixation is recommended. See Ebihara, 2005.
Optimal dilutions must be determined by the end user
Immunofluorescence:
It is difficult to grow the metapneumovirus in standard cell lines. LLC-MK2 can be used for culture; acetone fixation is recommended. See Ebihara, 2005.
Optimal dilutions must be determined by the end user
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
Biochem/physiol Actions
Recognizes Human Metapneumoviruses. Reacts against both A and B antigenic groups and subgroups 1 and 2.
Physical form
Format: Purified
Protein A Purified mouse immunoglobulin in 20 mM sodium phosphate, 250 mM NaCl, pH. 7.6, with 0.1% sodium azide as a preservative.
Protein A purified
Preparation Note
Maintain for 1 year at 2–8°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Analysis Note
Control
Metapneumovirus positive patient sample
Metapneumovirus positive patient sample
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Marlies Ballegeer et al.
mBio, 15(1), e0212223-e0212223 (2023-12-20)
Human metapneumovirus (hMPV) is an important respiratory pathogen for which no licensed antivirals or vaccines exist. Single-domain antibodies represent promising antiviral biologics that can be easily produced and formatted. We describe the isolation and detailed characterization of two hMPV-neutralizing single-domain
Antonella Bugatti et al.
Microorganisms, 8(6) (2020-06-04)
Human Metapneumovirus (HMPV) is a major cause of lower respiratory tract infections. HMPV infection has been hypothesized to alter dendritic cell (DC) immune response; however, many questions regarding HMPV pathogenesis within the infected lung remain unanswered. Here, we show that
Tomohiro Ogawa et al.
Frontiers in immunology, 12, 767666-767666 (2021-12-14)
Bronchial epithelial cells are front sentinels eliciting innate and adaptive immunity to respiratory viral pathogens. Recognition of viral double-stranded RNA induces antiviral interferon (IFN) responses in bronchial epithelial cells. Co-inhibitory molecules programmed cell death 1 ligand 1 (PD-L1) and ligand
James B Mahony
Expert review of anti-infective therapy, 8(11), 1273-1292 (2010-11-16)
The appearance of eight new respiratory viruses in the human population in the past 9 years, including two new pandemics (SARS coronavirus in 2003 and swine-origin influenza A/H1N1 in 2009), has tested the ability of virology laboratories to develop diagnostic
Detection of human metapneumovirus in clinical samples by immunofluorescence staining of shell vial centrifugation cultures prepared from three different cell lines.
Landry, ML; Ferguson, D; Cohen, S; Peret, TC; Erdman, DD
Journal of Clinical Microbiology null
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