MAB858-1
抗-RSV抗体，融合蛋白，所有A、B型毒株，克隆133-1H
ascites fluid, clone 133-1H, from mouse
别名:
RSV
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
133-1H, monoclonal
Species reactivity:
human
Application:
ELISA
immunofluorescence
immunofluorescence
Technique(s):
ELISA: suitable
immunofluorescence: suitable
immunofluorescence: suitable
Citations:
14
产品名称
抗-RSV抗体，融合蛋白，所有A、B型毒株，克隆133-1H, ascites fluid, clone 133-1H, from mouse
biological source
mouse
antibody form
ascites fluid
antibody product type
primary antibodies
clone
133-1H, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunofluorescence: suitable
isotype
IgG2a
shipped in
wet ice
Quality Level
Analysis Note
对照
RSV对照玻片，目录号5012-5
RSV对照玻片，目录号5012-5
Application
ELISA（1:800+）
间接免疫荧光（1:100-200+）（新鲜冷冻组织切片）
最终工作稀释度必须由最终用户确定。
间接免疫荧光（1:100-200+）（新鲜冷冻组织切片）
最终工作稀释度必须由最终用户确定。
研究子类别
传染病 - 病毒
传染病 - 病毒
研究类别
传染病
传染病
该抗RSV抗体，融合蛋白，所有A、B型毒株，克隆133-1H，经验证可用于ELISA、IF检测呼吸道合胞病毒。
Biochem/physiol Actions
针对RSV的47-49 kDa融合蛋白。 抗体MAB858-1可识别A和B RSV株。
Disclaimer
除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
General description
RSV是一种不稳定的副粘病毒，在组织培养中产生人类细胞的特征性融合-合胞体效应。已经鉴定出两种亚型A和B。亚型B的特征是该病毒的无症状株。更严重的临床疾病涉及亚型A株。
Immunogen
A2
表位：所有A & B型株
Other Notes
浓度：关于批次特定浓度请参见检验报告。
Physical form
未纯化
腹水，0.1%叠氮化钠作为防腐剂。
Preparation Note
自收到之日起在-20°C可稳定保存1年。分装保存以避免反复冻融。为了最大程度地回收产品，需在融化后和取下盖子之前将原始样品管进行离心。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_c
Not applicable
E K Park et al.
Molecules and cells, 12(1), 50-56 (2001-09-20)
Respiratory syncytial virus (RSV) is one of the principal agents of bronchiolitis and pneumonia in young children. Thus, there is a strong need to make a safe and effective vaccine against the RSV infection. DNA immunization is very effective at
Wy Ching Ng et al.
Journal of virology, 90(1), 206-221 (2015-10-16)
It is well established that influenza A virus (IAV) attachment to and infection of epithelial cells is dependent on sialic acid (SIA) at the cell surface, although the specific receptors that mediate IAV entry have not been defined and multiple
Bahar Ahani et al.
Nature communications, 14(1), 4347-4347 (2023-07-20)
Nirsevimab is a monoclonal antibody that binds to the respiratory syncytial virus (RSV) fusion protein. During the Phase 2b (NCT02878330) and MELODY (NCT03979313) clinical trials, infants received one dose of nirsevimab or placebo before their first RSV season. In this
Giulia Campanini et al.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 39(2), 119-124 (2007-04-25)
Human respiratory syncytial virus (hRSV) detection in nasopharyngeal aspirates (NPAs) from infants with acute respiratory tract infection (ARTI) does not prove the hRSV etiology of the current ARTI episode. HRSV RNA quantification may help in affording this issue. hRSV was
Bert Schepens et al.
EMBO molecular medicine, 6(11), 1436-1454 (2014-10-10)
Infections with human respiratory syncytial virus (HRSV) occur globally in all age groups and can have devastating consequences in young infants. We demonstrate that a vaccine based on the extracellular domain (SHe) of the small hydrophobic (SH) protein of HRSV
商品
呼吸道传染病由于其传染性强、传播速度快且发病率高，已成为我国重点防治的一类疾病。目前呼吸道病原体检测方法主要分为血清特异性抗体检测、抗原检测、多重核酸检测以及微生物检测系统。其中，相比于抗体检测，抗原检测在感染病毒初期、出现症状后即可做出检测，适用于疾病的早期诊断，对患者的治疗具有重要指导意义。
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