Anti-Measles Antibody, nucleoprotein, clone 83KKII

Measles is a highly contagious, acute febrile illness that has been one of the most common viral diseases of young children. Although measles has been effectively controlled in recent years by the use of live attenuated virus vaccines, measles continues to have a serious impact on human health as evidenced by its continued persistence in developing countries. Measles is characterized by a prodrome illness with rapidly rising fever that culminates in a generalized macular-papular rash. The appearance of Koplik′s spots on the mouth epithelium during or after the prodromal phase is pathognomonic for measles. The measles virus belongs to the family Paramyxoviridae, and is a member of the genus Morbillivirus. Measles is an enveloped, pleomorphic virus ranging from 100 to 250 nm in diameter with a single stranded linear RNA. Infected cells contain large amounts of nucleoprotein antigen which is the major internal protein of measles virus. Consequently, the dominant part of the antibody response to measles virus involves the nucleoprotein antigen.

Epitope: Nucleoprotein

Capture ELISA: A 1:5,000-1:10,000 dilution of a previous lot was used in ELISA.

Indirect Immunofluorescence: A previous lot of this antibody was used on indirect immunofluorescence.

Immunocytochemistry Analysis: A 1:100 dilution from a representative lot detected the measles nucleoprotein in cells infected with measles virus.

Optimal working dilutions must be determined by end user.

Research Category
Infectious Diseases

Research Sub Category
Infectious Diseases - Viral

This Anti-Measles Antibody, nucleoprotein, clone 83KKII is validated for use in ELISA, IF for the detection of Measles.

MAB8906 recognizes the measles nucleoprotein by capture EIA.

Format: Purified

Protein A purified

Purified mouse monoclonal IgG in buffer containing liquid in PBS with 0.1% sodium azide.

Stable for 1 year at from date of receipt.

Control
Measles Control Slides, Catalogue Number 5031-5

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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