MABE450
Anti-TAF15, clone 8TA-2B10 Antibody
ascites fluid, clone 8TA-2B10, from mouse
别名:
TATA-binding protein-associated factor 2N, 68 kDa TATA-binding protein-associated factor, TAF(II)68, TAFII68, RNA-binding protein 56
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
8TA-2B10, monoclonal
Application:
immunoprecipitation (IP)
western blot
western blot
Species reactivity:
rat, mouse, human
Citations:
1
Technique(s):
immunoprecipitation (IP): suitable
western blot: suitable
western blot: suitable
Uniprot accession no.:
产品名称
Anti-TAF15, clone 8TA-2B10 Antibody, ascites fluid, clone 8TA-2B10, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
ascites fluid
antibody product type
primary antibodies
clone
8TA-2B10, monoclonal
species reactivity
rat, mouse, human
technique(s)
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TAF15(8148)
Analysis Note
Evaluated by Western Blotting in A431 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected TAF15 in 10 µg of A431 cell lysate.
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected TAF15 in 10 µg of A431 cell lysate.
Application
Anti-TAF15 antibody, clone 8TA-2B10 is an antibody against TAF15 for use in western blotting & IP.
General description
TAF15, also known as TATA-binding protein-associated factor 2N, or 68 kDa TATA-binding protein-associated factor, or TAF(II)68, TAFII68, or RNA-binding protein 56, and encoded by the gene TAF15/RBP56/TAF2N, is a RNA and ssDNA binding protein important in transcription initiation. TAF15 aligns with the RNA polymerase II (Pol II) multiprotein complex that together with other proteins like TBP initiates transcription. TAF15 is ubiquitously expressed, and TAF15 shuttles from the nucleus to the cytoplasm upon activation; methylation of TAF15 appears to guide nuclear localization and transcriptional activity. Translocations involving the TAF15 gene may play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene are associated with amyotrophic lateral sclerosis (ALS) diseases.
~68 kDa observed
Physical form
Mouse monoclonal IgG1κ ascites without preservatives.
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存储类别
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Yan Wang et al.
Oncotarget, 8(67), 111866-111881 (2018-01-18)
S-adenosyl methionine (SAM) is a ubiquitous methyl donor that was reported to have chemo- protective activity against liver cancer, however the molecular footprint of SAM is unknown. We show here that SAM selectively inhibits growth, transformation and invasiveness of hepatocellular
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