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Merck
CN

MABF106

抗-蝰蛇毒素抗体,克隆MaP.VIP

clone MaP.VIP, from mouse

别名:

Radical S-adenosyl methionine domain-containing protein 2, Cytomegalovirus-induced gene 5 protein, Viperin, Virus inhibitory protein,endoplasmic reticulum-associated, interferon-inducible

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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产品名称

抗-蝰蛇毒素抗体,克隆MaP.VIP, clone MaP.VIP, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

MaP.VIP, monoclonal

species reactivity

human, rat, mouse

technique(s)

flow cytometry: suitable
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

isotype

IgG2aκ

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... RSAD2(91543)

Analysis Note

对照
IFN γ和LPS刺激的小鼠巨噬细胞
通过蛋白质印迹法在IFNγ和LPS刺激的小鼠巨噬细胞中进行评价。

蛋白质印迹分析:1 µg/mL的该抗体在用IFNγ和LPS刺激的10 µg小鼠巨噬细胞中检测到Viperin。

Application

免疫组织化学分析: 一个代表性批次以1:500-1:1,000稀释度在人结肠和大鼠肝组织中检测到Viperin。

免疫沉淀分析: 一个代表性批次被独立实验室用于HepG2细胞裂解物(Hinson,E.,et al.(2008).JBC.284(7):4705–4712)。

流式细胞术分析: 一个代表性批次被独立实验室用于小鼠肝脏、脾脏、肺和淋巴结细胞(Hinson,E.,et al.(2010).J. Immunol. 184:5723-5731)。

免疫细胞化学分析: 一个代表性批次被独立实验室用于小鼠脾细胞(Hinson,E.,et al.(2010).J. Immunol. 184:5723-5731)。
抗Viperin抗体,克隆MaP.VIP检测Viperin水平,&已发布&验证可用于WB、IH、FC、IP&IC。
研究子类别
免疫球蛋白 & 免疫学
研究类别
炎症 & 免疫学

Disclaimer

除非我们的目录或产品随附的其他公司文件中另有说明,否则我们的产品预期仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。

General description

病毒抑制蛋白内质网相关干扰素诱导型(Viperin)属于RSAD2家族,可被I型和II型干扰素高度诱导,但在单核细胞系中观察到很少或没有诱导。 研究表明,Viperin参与宿主的抗病毒反应,因为从病毒感染中观察到了Viperin的诱导。 研究还表明,Viperin通过影响脂筏的形成,通过改变质膜流动性来破坏流感病毒从质膜的释放,从而抑制流感病毒的复制。脂筏是用于流感病毒出芽的已知耐洗涤剂的微结构域位点。
观测分子量〜42 kDa

Immunogen

对应于人Viperin的重组蛋白。

Other Notes

浓度:关于批次特定浓度请参见检验报告。

Physical form

形式:纯化
纯化的小鼠单克隆IgG2aκ,溶于含0.1 M Tris-甘氨酸(pH 7.4)、150 mM NaCl和0.05%叠氮化钠的缓冲液中。
纯化蛋白G

Preparation Note

自接收之日起,在2-8°C下可稳定保存1年。

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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