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Merck
CN

MABF505

Anti-CAMK4, clone 8C5B8 Antibody

clone 8C5B8, from mouse

别名:

Calcium/calmodulin-dependent protein kinase type IV, CaMK IV, CAMK4

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
8C5B8, monoclonal
Application:
ELISA
immunofluorescence
immunohistochemistry
western blot
Species reactivity:
human
Citations:
Technique(s):
ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable
Uniprot accession no.:
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产品名称

Anti-CAMK4, clone 8C5B8 Antibody, clone 8C5B8, from mouse

biological source

mouse

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

8C5B8, monoclonal

species reactivity

human

technique(s)

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG1

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... CAMK4(814)

Analysis Note

Evaluated by Western Blotting in SK-N-SH, Raji and HeLa cell lysates.

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected CAMK4 in SK-N-SH, Raji and HeLa cell lysates.

Application

Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected CAMK4 in ovarian and rectum cancer tissues.

Immunofluorescence Analysis: A 1:200-1,000 dilution from a representative lot detected CAMK4 in HepG2 cells.

ELISA: A representative lot detected control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
This Anti-CAMK4, clone 8C5B8 Antibody is validated for use in western blotting, IHC, immunofluorescence & ELISA for the detection of CAMK4.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Calcium/calmodulin-dependent protein kinase type IV (CaMK IV), also known as CaM kinase-GR, and encoded by the gene name CAMK4 or CAMK or CAMK-GR or CAMKIV, is a multifunctional serine/threonine protein kinase with limited tissue distribution, that has been implicated in transcriptional regulation in lymphocytes, neurons and male germ cells. CAMK4 is localized in hippocampal neuron nuclei and is associated with chromatin and the nuclear matrix in spermatids. Expression in CAMK4 can be found in brain, thymus, CD4 T-cells, testis, and epithelial ovarian cancer tissue. CAMK4 can be phosphorylated by CaMKK1 and CaMKK2 on Thr200 and dephosphorylated by protein phosphatase 2A.
~57 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Immunogen

Purified recombinant fragment of human CAMK4 expressed in E. Coli

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Format: Purified
Protein G Purified
Purified mouse monoclonal in PBS containing up to 0.1% sodium azide and 0.5% protein stabilizer.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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