Gamma-synuclein is one four proteins in the synuclein family, Gamma-synuclein appears to play a role in neurofilament network integrity and interaction. Gamma synuclein is important for axonal architecture and maintenance and the protein interacts with both the MAPK and ELK-1 signaling networks. Gamma synuclein is a cytoplasmically associated protein that is also strongly associated with cytoskeletal elements. During cell division, gamma synuclein is associated with the poles of the spindle and interruption causes defects in cytokinesis. Gamma synuclein is highly expressed in the brain but can also be found expressed in the heart, skeletal muscle, colon, and gonads. Gamma synuclein is also expressed in many invasive cancers.

~15 kDa observed

GST-tagged recombinant protein corresponding to human Gamma-synuclein (SNCG).

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

This Anti-Gamma-synuclein (SNCG), clone 3D2.1 Antibody is validated for use in Western Blotting for the detection of Gamma-synuclein (SNCG).

Protein G Purified

Format: Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Evaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Gamma-synuclein (SNCG) in 10 µg of human cortex tissue lysate.

Concentration: Please refer to lot specific datasheet.

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