MABT205
抗-α-微管蛋白抗体，克隆DM1A
clone DM1A, from mouse
别名:
Tubulin alpha-1 chain
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
DM1A, monoclonal
Application:
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Species reactivity:
mouse, human
Citations:
45
Technique(s):
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
immunohistochemistry: suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗-α-微管蛋白抗体，克隆DM1A, clone DM1A, from mouse
biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
DM1A, monoclonal
species reactivity
mouse, human
species reactivity (predicted by homology)
chicken (based on 100% sequence homology)
technique(s)
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
isotype
IgG1κ
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... TUBA1A(7846)
Analysis Note
对照
HeLa细胞裂解物。
HeLa细胞裂解物。
通过蛋白质印迹法在HeLa细胞裂解物中进行评估。
蛋白质印迹分析：0.01 µg/mL的该抗体在10 µg HeLa细胞裂解物中检测到α-微管蛋白。
蛋白质印迹分析：0.01 µg/mL的该抗体在10 µg HeLa细胞裂解物中检测到α-微管蛋白。
Application
免疫细胞化学分析：一个代表性批次以1:500稀释度在NIH/3T3、A431和HeLa细胞中检测到的α-微管蛋白。
免疫组织化学分析：一个代表性批次以1:10,000稀释度在正常人脑组织、人脑癌组织、正常大鼠海马组织和正常大鼠小脑组织中检测到α-微管蛋白。
免疫组织化学分析：一个代表性批次以1:10,000稀释度在正常人脑组织、人脑癌组织、正常大鼠海马组织和正常大鼠小脑组织中检测到α-微管蛋白。
研究子类别
细胞骨架
细胞骨架
研究类别
细胞结构
细胞结构
该抗α-微管蛋白抗体（克隆DM1A）经验证可用于蛋白质印迹、ICC、IHC检测α-微管蛋白。
Disclaimer
除非我们的目录或产品随附的其他公司文件中另有说明，否则我们的产品预期仅用于研究用途，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
General description
微管蛋白是细胞骨架的主要成分之一。它是由互锁的α和β链组成的异二聚体结构。像其他细胞骨架蛋白一样，微管蛋白会根据细胞环境而发生动态变化，这是由GDP/GTP的结合和释放介导的。微管蛋白也可能经历翻译后修饰，并且对于细胞运输和有丝分裂过程至关重要。
观测分子量〜60 kDa。Uniprot描述的分子量约为46 kDA，但由于翻译后修饰而可能更高。在一些细胞裂解物中观察到该蛋白的分子量约为55 kDa（Saugstad，J.A.，et al.（2002）.J Neurochem.80（6）:980-988.）。
Immunogen
土鸡脑微管。
Other Notes
替代：04-1117
浓度：关于批次特定浓度请参见检验报告。
Physical form
形式：纯化
纯化的小鼠单克隆IgG1κ，溶于含0.1 M Tris-甘氨酸（pH 7.4）、150 mM NaCl和0.05%叠氮化钠的缓冲液中。
纯化蛋白G
Preparation Note
自接收之日起，在2-8°C下可稳定保存1年。
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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