MABT42
Anti-Integrin beta-2 (CD18) Antibody, clone M18/2
clone M18/2, from rat
别名:
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), integrin beta chain, beta 2, complement receptor C3 beta-subunit, leukocyte cell adhesion molecule CD18, integrin beta-2, Complement receptor C3 subunit beta, Cell surface adhesion glyco
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
M18/2, monoclonal
Application:
FACS, IP
Citations:
2
biological source
rat
Quality Segment
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
M18/2, monoclonal
species reactivity
mouse
technique(s)
flow cytometry: suitable, immunoprecipitation (IP): suitable
isotype
IgG2aκ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
mouse ... Itgb2(16414)
General description
85 kDa calculated
Integrin beta-2, also known as CD18, is an adhesion receptor in neutrophils that interacts with cytohesin-1 intracellularly. Integrin beta is instrumental in activation-dependent adhesion and adhesion-dependent signaling. Expression of integrin beta-2 has a positive correlation with patient survival from malignant B cell lymphoma.
Immunogen
Whole B10 mouse spleen cells enriched with T-cells.
Application
Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP (Sanchez-Madrid, F., et al. (1983). J. ExP. MED. 158:586-602).
Inhibition Analysis: A previous lot of this antibody was shown to inhibit lymphoma metastasis (Zahalka, M. A. et al. (1993) J. Immunol. 150, 4466).
Inhibition Analysis: A previous lot of this antibody was shown to inhibit lymphoma metastasis (Zahalka, M. A. et al. (1993) J. Immunol. 150, 4466).
This Anti-Integrin beta-2 (CD18) Antibody, clone M18/2 is validated for use in FC, IP for the detection of Integrin beta-2 (CD18).
Physical form
Format: Purified
Analysis Note
Control
Mouse EL4 cells
Mouse EL4 cells
Evaluated by Flow Cytometry in mouse EL4 cells.
Flow Cytometry Analysis: 10 µg of this antibody detected Integrin beta-2 in mouse EL4 cells.
Flow Cytometry Analysis: 10 µg of this antibody detected Integrin beta-2 in mouse EL4 cells.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable