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MABT84

Anti-Aggrecan Antibody, clone 1-C-6

Name: Anti-Aggrecan Antibody, clone 1-C-6
Brand: MM

clone 1-C-6, from mouse

别名:

Aggrecan core protein, Cartilage-specific proteoglycan core protein, CSPCP

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关于此项目

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

1-C-6, monoclonal

Application:

IHC, WB

Citations:

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属性

biological source

mouse

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1-C-6, monoclonal

species reactivity

mouse, rat, bovine

technique(s)

immunohistochemistry: suitable, western blot: suitable

isotype

IgG1κ

NCBI accession no.

NP_071526

UniProt accession no.

P07897

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ACAN(176)

说明

General description

Aggregating chondroitin sulfate proteoglycan or aggrecan, is one of the most studied proteoglycans. Many individual monomers of aggrecan bind to hyaluronic acid to form an aggregate, the monomer is known as aggrecan. The aggregates are comprised of up to 100 monomers attached to a single chain of hyaluronic acid. The high content of negatively charged polysaccharide chains contributes to the osmotic swelling of cartilage and in combination with intact collagen fibers results in articular cartilage resistance to compressive forces and high tensile strength. Aggrecan is abundant in articular cartilage and compromises 10% of its dry weight.

Various

Immunogen

Reduced and alkylated Aggrecan isolated from Swarm Rat Chondrosarcoma

Application

This Anti-Aggrecan Antibody, clone 1-C-6 is validated for use in IH, WB for the detection of Aggrecan.

Western Blot Analysis: 1 µg/mL from a representative lot detected Aggrecan on 10 µg of A1D4 protein fraction from Bovine tissue.

Physical form

Format: Purified

Analysis Note

Control
Normal mouse cartilage and normal rat cartilage tissues

Evaluated by Immunohistochemistry in normal mouse cartilage and normal rat cartilage tissues.

Immunohistochemistry Analysis: A 1:1,000 dilution of this antibody detected Aggrecan in normal mouse cartilage and normal rat cartilage tissues.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c