产品名称
Multiscreen® 96孔板，聚碳酸酯膜, pore size 5 μm, sterile
description
Clear, Sterile, 5.0 µm pore size, Polycarbonate (PC) membrane, 10 plates
sterility
sterile
Quality Level
material
clear polystyrene plate
flat bottom wells
polycarbonate membrane
usage
Manual
feature
hydrophilic
lid
packaging
pkg of 10 plates
manufacturer/tradename
MultiScreen®
technique(s)
DNA purification: suitable
cell based assay: suitable
cell migration: suitable
filtration area
0.28 cm2
plate size
96 wells
well maximum volume
350 μL
working volume
50-250 μL
pore size
5 μm pore size
binding type
Tissue Culture (TC)-treated surface
compatibility
manifold only
shipped in
ambient
Application
MultiScreen® 96孔迁移侵袭和趋化滤板已用于transwell/细胞迁移检测，使用：
- 经白细胞介素(IL)-4-和IL-12处理的T细胞
- THP-1（人急性单核细胞白血病细胞系）
- 体外激活、纯化和维持半乳糖凝集素-3缺陷(gal3)-/-和gal3+/+分化4 (CD4)+ OTII T细胞簇
General description
MultiScreen®-MIC (Migration, Invasion, Chemotaxis)平板是一种96孔的一次性装置，用于在药物发现中筛选蛋白库和化合物先导物的功能检测。它旨在使用单个设备支持高通量细胞功能检测，如悬浮和/或贴壁细胞系的迁移、侵袭和趋化性。该平板可用于执行和量化细胞迁移或入侵跨涂层或未涂层膜，以响应浓度梯度。MultiScreen-MIC平板具有多种孔径，可用于多种细胞系的MIC测定，并且仅用于单次使用。
Legal Information
MULTISCREEN is a registered trademark of Merck KGaA, Darmstadt, Germany
Jeremy Green et al.
Journal of medicinal chemistry, 58(12), 5028-5037 (2015-06-04)
The Rho kinases (ROCK1 and ROCK2) are highly homologous serine/threonine kinases that act on substrates associated with cellular motility, morphology, and contraction and are of therapeutic interest in diseases associated with cellular migration and contraction, such as hypertension, glaucoma, and
Huan-Yuan Chen et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(34), 14496-14501 (2009-08-27)
We have investigated the function of endogenous galectin-3 in T cells. Galectin-3-deficient (gal3(-/-)) CD4(+) T cells secreted more IFN-gamma and IL-4 than gal3(+/+)CD4(+) T cells after T-cell receptor (TCR) engagement. Galectin-3 was recruited to the cytoplasmic side of the immunological
Tilo Biedermann et al.
Journal of immunology (Baltimore, Md. : 1950), 177(6), 3763-3770 (2006-09-05)
Distinct pattern of homing receptors determines the tissue preference for T cells to exert their effector functions. This homing competence is mostly determined early during T cell activation of naive T cells. In contrast, mechanisms governing the acquisition of particular
相关内容
MultiScreen® Filter Plates
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持