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Merck
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MCVD2MAG-77K

MILLIPLEX® Mouse Cardiovascular Disease Panel

Configurable Mouse CVD 9-Plex Panel 2

别名:

CVD assay snapshot mouse, CVD multiplex product sheet mouse, cardiac injury detection panel mouse, cardiovascular biomarker listing mouse, endothelial activation biomarker kit mouse, mouse CVD assay overview, mouse cardiac health research tool, mouse cardiovascular panel summary, mouse vascular biomarker panel, vascular inflammation product info mouse

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UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000
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Quality Level

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

inter-assay cv: <20%
intra-assay cv: <10%, accuracy: 84-106%, standard curve range: 137-100,000 pg/mL
(CD40L), standard curve range: 14-10,000 pg/mL
(Endocan-1), standard curve range: 274-200,000 pg/mL
(Follistatin), standard curve range: 34-25,000 pg/mL
(CXCL16, Oncostatin M), standard curve range: 4-3,000 pg/mL
(PIGF-2), standard curve range: 686-500,000 pg/mL
(LIGHT, Troponin I), standard curve range: 69-50,000 pg/mL
(Troponin T)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

species reactivity

mouse

technique(s)

multiplexing: suitable

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General description

Cardiovascular disease in mouse models is influenced by inflammatory, ischemic, and remodeling processes. This panel—sCD40L, CXCL16, Endocan-1, Follistatin, LIGHT, Oncostatin M, Placental Growth Factor 2, Troponin I, and Troponin T—captures key indicators of vascular inflammation, endothelial dysfunction, and cardiac injury. The MILLIPLEX® Mouse CVD Panel 2 enables multiplexed quantification of these biomarkers in mouse serum or plasma, supporting preclinical research in cardiovascular pathology and therapeutic development.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 9 analytes in mouse serum, plasma, or cell culture supernatants.

Analytes Included: sCD40L, CXCL16, Endocan-1 (ESM-1), Follistatin (FST), LIGHT, Oncostatin M (OSM), Placental Growth Factor 2 (PlGF-2), Troponin I (TnI), Troponin T (TnT)

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Features:

  • Targets biomarkers involved in endothelial activation, inflammation, and cardiac injury
  • Includes 9 analytes relevant to mouse cardiovascular health and immune response
  • Multiplex format enables simultaneous detection from minimal sample volume
  • Compatible with mouse serum, plasma, and cell/tissue culture supernatants
  • Designed for research in atherosclerosis, myocardial injury, and vascular inflammation
Benefits:

  • Provides a comprehensive profile of vascular and cardiac biomarkers in mouse models
  • Supports investigation of inflammatory and ischemic mechanisms in cardiovascular disease
  • Facilitates evaluation of therapeutic interventions and disease progression
  • Enables high-throughput analysis with reduced sample and reagent use
  • Delivers reproducible, sensitive results for preclinical and translational research

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

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David Sánchez-Infantes et al.
Obesity (Silver Spring, Md.), 25(1), 85-93 (2016-10-06)
Since oncostatin m (OSM) is elevated in adipose tissue in conditions of obesity and type 2 diabetes in mice and humans, the aim of this study was to determine whether this cytokine plays a crucial role in the impairment of

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