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Merck
CN

MX0475

甲醇

≥99.8% (GC), suitable for HPLC, meets USP/NF

别名:

木酒精

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线性分子式:
CH3OH
化学文摘社编号:
67-56-1
分子量:
32.04
UNSPSC Code:
41116121
EC Index Number:
200-659-6
MDL number:
MFCD00004595
Beilstein/REAXYS Number:
1098229
Grade:
HPLC grade
Assay:
≥99.8% (GC)
Technique(s):
HPLC: suitable
Application(s):
PFAS testing
Bp:
64.7 °C (lit.)
Vapor pressure:
128 hPa ( 20 °C)
410 mmHg ( 50 °C)
97.68 mmHg ( 20 °C)

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产品名称

甲醇, HPLC, Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs

SMILES string

CO

InChI key

OKKJLVBELUTLKV-UHFFFAOYSA-N

InChI

1S/CH4O/c1-2/h2H,1H3

grade

HPLC grade

agency

meets USP/NF

vapor density

1.11 (vs air)

vapor pressure

128 hPa ( 20 °C)
410 mmHg ( 50 °C)
97.68 mmHg ( 20 °C)

assay

≥99.8% (GC)

form

liquid

autoignition temp.

725 °F

expl. lim.

36 %

technique(s)

HPLC: suitable

impurities

≤0.0002 meq/g Titrable base
≤0.0003 meq/g Titrable acid
≤0.001% Carbonyl (acetone,formaldehyde,acetaldehyde)
≤0.05% Water (H2O)

evapn. residue

≤2 ppm

color

APHA: ≤10

refractive index

n20/D 1.329 (lit.)

bp

64.7 °C (lit.)

mp

−98 °C (lit.)

transition temp

flash point 9.7 °C

density

0.791 g/mL at 25 °C (lit.)

UV cutoff

≤205 nm

UV absorption

λ: 205 nm Amax: ≤1.00
λ: 210 nm Amax: ≤0.80
λ: 220 nm Amax: ≤0.40
λ: 230 nm Amax: ≤0.20
λ: 240 nm Amax: ≤0.10
λ: 260 nm Amax: ≤0.04
λ: 280-400 nm Amax: ≤0.01

application(s)

PFAS testing

format

neat

shipped in

ambient

storage temp.

room temp

Quality Level

100
300

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Analysis Note

AppearanceClear liquid free from particulatesAssay (GC)99.8% minCarbonyl (acetone,formaldehyde,acetaldehyde)0.001% maxColor (APHA)10 maxEvaporation residue2ppm maxFiltered through 0.2 µm filterTo pass testGradient at 254 nm0.005AU maxIdentity (IR-spectrum)ConformsSolubility in waterTo pass testSubstances darkened by sulfuric acidTo pass testSubstances reducing permanganateTo pass testTitrable acid0.0003meq/g maxTitrable base0.0002meq/g maxUV Abs. at 205 nm1.00AU maxUV Abs. at 210 nm0.80AU maxUV Abs. at 220 nm0.40AU maxUV Abs. at 230 nm0.20AU maxUV Abs. at 240 nm0.10AU maxUV Abs. at 260 nm0.04AU maxUV Abs. at 280 - 400 nm0.01AU maxUV Cut-off205nm maxWater (H2O)0.05% max
Evaporation Number: 1.9

Application

HPLC, Meets ACS Specifications, Meets Reagent Specifications for testing USP/NF monographs
MX0475P-6 and MX0475P-1 are packaged in poly coated glass bottles
MX0475-NP10 is sold as 2 x 10 L
Methanol can be used as:
  • A solvent for the extraction of pesticides from soil samples.
  • An organic modifier in the quantification of esculin in pharmaceutical formulations via reverse-phase high-performance liquid chromatography (RP-HPLC).

General description

Methanol is suitable for isocratic HPLC, meets ACS specifications for testing USP/NF testing monographs. It is extensively utilized in High-Performance Liquid Chromatography (HPLC) due to its excellent solvation properties and high miscibility with both water and organic solvents, thus making it an effective solvent for preparing mobile phases that enhance the separation and sensitivity of analyte detection.

Packaging

M-Bottle for Solvents
As a global leader in lab reagents, we are constantly looking for new ways to optimize the safety of our products. The newly developed 4L solvent bottle design features advanced sealing technology that eliminates leaks to make the handling of solvents safer and more convenient than ever before.
See all the new features here!

Preparation Note

Product filtered through a 0.2 μm filter

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

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Development of a robust and reliable reverse-phase high-performance liquid chromatography (RP-HPLC) method using analytical quality by design principles for the accurate determination of esculin in its bulk form
Patil S, et al.
Future Journal of Pharmaceutical Sciences, 9, 69-69 (2023)
Extraction of pesticides from soil using direct-immersion SPME LC-Tips followed by GC-MS/MS: Evaluation and proof-of-concept
Brinco J, et al.
Journal of Chromatography A, 1735, 465295-465295 (2024)

实验方案

Protocol for In-vitro Permeation Testing Using Strat-M® Membranes

Strat-M® synthetic membrane mimics the human skin for In-vitro permeation testing (IVPT) of topical and transdermal formulations

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