MILLIPLEX^® Non-Human Primate Cytokine/Chemokine/Growth Factor Panel A

Cytokines are small proteins secreted by immune cells that regulate immune responses, hematopoiesis, and lymphocyte development, including interleukins, interferons, and chemokines. Growth factors, which promote cell growth and proliferation, share structural and functional similarities with cytokines and act through specific receptors on target cells. Unlike hormones produced by specialized glands, both cytokines and growth factors can be secreted by various cell types, and their tightly regulated expression is crucial; dysregulation can lead to diseases such as infections, autoimmune disorders, and cancer. Research on these molecules is essential for understanding the immune system and developing therapeutic strategies, with non-human primates serving as important models due to their genetic similarity to humans.

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 48 analytes in non-human primate serum, plasma, and cell culture supernatants.

Analytes included: BCA-1, sCD137, CD40L, Eotaxin, sFASL, FGF-2, Fractalkine, G-CSF, GM-CSF, Granzyme A, Granzyme B, IFNα2, IFNγ, IL-1α, IL-1β, IL-1RA, IL-2, IL-4, IL-5, IL-6, IL-7, IL-8, IL-10, IL-12 (p70), IL-15, IL-16, IL-17A, IL-17E, IL-18, IL-21, IL-22, IL-23, IL-28A, IL-31, IL-33, IP-10, I-TAC, MCP-1, MIG, MIP-1α, MIP-1β, MIP-3α, Perforin, RANTES, TGFα, TNFα, TNFβ, VEGF-A NOTE: RANTES cannot be plexed with other cytokines in this panel due to a required 1:100 dilution of plasma/serum samples. This premixed panel comes with a RANTES bead, so please plan your samples accordingly.

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Tailored for Non-Human Primate Research: Specifically developed to support studies involving non-human primate samples, ensuring accurate and relevant data for translational and preclinical research.

Space-Saving Bulk Packaging: Reduce cold storage demands with compact bulk premixed kits—perfect for labs with limited freezer or fridge space.

Flexible Incubation Options: Offers both rapid (2 hour) and overnight incubation protocols to suit different workflow needs and sensitivity requirements.

Low Sample Volume Requirement: Requires minimal sample input (25µL), preserving valuable biological material and enabling repeated testing.

Comprehensive Coverage: Largest commercially available multiplex panel specifically designed for NHP research.

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.