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Merck
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About This Item

UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.84

质量水平

种属反应性

rat

制造商/商品名称

Milliplex®

assay range

accuracy: 88-105%
sensitivity: 0.8-42.2 pg/mL
standard curve range: 0.4-1,500 pg/mL
(PTH)

standard curve range: 10-40,000 pg/mL
(ACTH and OPG)

standard curve range: 12-50,000 pg/mL
(DKK-1)

standard curve range: 22-90,000 pg/mL
(FGF-23)

standard curve range: 31-125,000 pg/mL
(Insulin)

standard curve range: 5-20,000 pg/mL
(SOST)

standard curve range: 7-30,000 pg/mL
(Leptin)

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

wet ice

一般描述

Bone metabolism is the dynamic process of ongoing bone deposition and resorption, controlled by osteoblasts, osteocytes, and osteoclasts. While osteoblasts and osteocytes (osteoblasts surrounded by matrix) are responsible for bone deposition, osteoclasts are responsible for bone resorption. Both are required to maintain bone structure, as well as an adequate supply of calcium. To maintain this metabolic balance, these cells rely on complex signaling pathways involving hormones and cytokines to achieve the appropriate rates of growth and differentiation.

MILLIPLEX® Rat Bone Panel 1 is an 8-plex kit to be used for the simultaneous quantification of any or all of the following in rat serum and plasma samples: ACTH, OPG, Insulin, Leptin, PTH, DKK1, SOST, and FGF23. This kit uses a 96-well format, contains a lyophilized standard cocktail, two internal assay quality controls and can measure up to 38 samples in duplicate.

The Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.

Panel Type: Bone

特异性

Cross Reactivty
The antibody pairs in each panel do not show cross reactivity to the other analytes within the panel

应用

  • Analytes: ACTH, DKK1, FGF-23, Insulin, Leptin, Osteoprotegerin (OPG), PTH, Sclerostin (SOST)
  • Recommended Sample Type: Rat serum or plasma
  • Recommended Sample Dilution: 25 μL per well of neat serum or plasma
  • Assay Run Time: Overnight (16-18 hours) at 2-8°C is recommended; alternately incubate for 2 hours at room temperature (20-25°C).
  • Research Category: Bone
  • Research Subcategory: Metabolism

特点和优势

Design your multiplex kit by choosing available analytes within this panel.

其他说明

Please contact Technical Service for linearity of dilution.

法律信息

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

象形图

Skull and crossbonesEnvironment

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects


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