Merck
CN
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文件

安全信息

RKTX1MAG-37K

Millipore

MILLIPLEX® 大鼠肾毒性磁珠面板1-毒性多重测定

The analytes available for this multiplex kit are: Clusterin, GSTα, IP-10, KIM-1, OPN - Osteopontin, TIMP-1, VEGF.

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eCl@ss:
32161000

质量水平

200

种属反应性

rat

制造商/商品名称

Milliplex®

assay range

accuracy: 70-123%
standard curve range: 0.03-20 ng/mL
(IP-10, KIM-1, OPN)
standard curve range: 0.03-20 ng/mL
(VEGF)
standard curve range: 0.27-200 ng/mL
(TIMP-1)
standard curve range: 2.06-1500 ng/mL
(Clusterin)
standard curve range: 4.12-3000 ng/mL
(GSTα)
inter-assay cv: <10%
intra-assay cv: <15%
(All other analytes)
inter-assay cv: <20%
intra-assay cv: <30%
(GSTα)

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

wet ice

相关类别

一般描述

MILLIPLEX® 大鼠肾毒性磁珠面板1 & 2，加上微珠形式的Luminex® xMAP®平台，使您能够专注于发现，从而获得理想的速度和灵敏度优势，允许同时定量多重检测多种分析物，从而可以显著提高生产力。

面板类型：毒性

应用

  • 分析物：Clusterin GSTα IP-10 KIM-1 OPN - 骨桥蛋白TIMP-1 VEGF
  • 推荐的样品类型：尿液
  • 推荐的样品稀释度：1:2
  • 分析运行时间：过夜

特点和优势

通过在此面板中选择可用的分析物来设计多重试剂盒。

其他说明

灵敏度：有关单个分析物的灵敏度，请参见试剂盒方案。

法律信息

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

象形图

Skull and crossbonesEnvironment
GHS06,GHS09

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

法规信息

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Javad Habibi et al.
Cardiovascular diabetology, 18(1), 40-40 (2019-03-27)
Diabetic nephropathy (DN) is characterized by glomerular and tubulointerstitial injury, proteinuria and remodeling. Here we examined whether the combination of an inhibitor of neprilysin (sacubitril), a natriuretic peptide-degrading enzyme, and an angiotensin II type 1 receptor blocker (valsartan), suppresses renal
Kidney biomarkers in MCPA-induced acute kidney injury in rats: reduced clearance enhances early biomarker performance.
Wunnapuk, K; Liu, X; Gobe, GC; Endre, ZH; Peake, PW; Grice, JE; Roberts, MS; Buckley, NA
Toxicology Letters null
Iwan P Williams et al.
mAbs, 12(1), 1685349-1685349 (2019-11-27)
IgE monoclonal antibodies hold great potential for cancer therapy. Preclinical in vivo systems, particularly those in which the antibody recognizes the host species target antigen and binds to cognate Fc receptors, are often the closest approximation to human exposure and
Nadeeka S Udawatte et al.
Frontiers in pharmacology, 11, 511-511 (2020-05-12)
Candida albicans is the major fungal species associated with superficial mucosal infections such as oral candidiasis as well as systemic mycoses with high morbidity and mortality. On top of the rising drug resistance, currently available antifungal agents have significant adverse
Klintean Wunnapuk et al.
Toxicology letters, 225(1), 192-200 (2013-12-24)
Accidental or intentional ingestion of glyphosate surfactant-based herbicides, like Roundup(®), leads to nephrotoxicity as well as death. In this study, a panel of kidney injury biomarkers was evaluated in terms of suitability to detect acute kidney injury and dysfunction. The

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