产品名称
MILLIPLEX® Rat/Mouse Neuropeptide Panel, Configurable Rat/Mouse Neuropeptide 5-Plex Panel
packaging
1 ea of
assay range
accuracy: 107-135%
(Rat)
standard curve range: 14-100,000 pg/mL
(Oxytocin)
standard curve range: 27-20,000 pg/mL
(Neurotensin)
standard curve range: 3-2,000 pg/mL
(Substance P)
standard curve range: 41-30,000 pg/mL
(α-MSH)
standard curve range: 69-50,000 pg/mL
(β-Endorphine)
technique(s)
multiplexing: suitable
input
cell culture supernatant(s)
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
species reactivity
mouse, rat
manufacturer/tradename
Milliplex®
Quality Level
Legal Information
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
Luminex is a registered trademark of Luminex Corp
xMAP is a registered trademark of Luminex Corp
Application
MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 5 analytes in rat and mouse serum, plasma, and cell culture supernatants and lysates.
Analytes included: α-MSH, β-Endorphin, Neurotensin, Oxytocin, Substance P. Note: Serum and plasma samples require extraction using acetonitrile precipitation or an extraction plate. See kit protocol for details. Note: This is a competitive assay.
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Analytes included: α-MSH, β-Endorphin, Neurotensin, Oxytocin, Substance P. Note: Serum and plasma samples require extraction using acetonitrile precipitation or an extraction plate. See kit protocol for details. Note: This is a competitive assay.
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Disclaimer
For research use only. Not for use in diagnostic procedures.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Features and Benefits
Comprehensive Neuropeptide Coverage: Quantify key neuropeptides such as α-MSH, β-Endorphin, and Oxytocin simultaneously, enhancing your research into neurobiology and disease mechanisms.
Sensitivity and Precision: Achieve reliable detection with precision and accuracy, ensuring confidence in your results across various sample types.
Customizable Panels: Tailor your kit to include any combination of analytes, allowing for a focused approach that meets your specific research needs.
Streamlined Workflow: The all-in-one kit format includes all necessary reagents, simplifying the setup and execution of your assays while saving valuable research time.
Robust Technical Support: Benefit from dedicated support teams, including expert sales specialists and field application scientists.
Sensitivity and Precision: Achieve reliable detection with precision and accuracy, ensuring confidence in your results across various sample types.
Customizable Panels: Tailor your kit to include any combination of analytes, allowing for a focused approach that meets your specific research needs.
Streamlined Workflow: The all-in-one kit format includes all necessary reagents, simplifying the setup and execution of your assays while saving valuable research time.
Robust Technical Support: Benefit from dedicated support teams, including expert sales specialists and field application scientists.
General description
The central nervous system comprises billions of neurons and glial cells that communicate through various chemical signals, including neurotransmitters and neuropeptides. Neuropeptides, secreted from both the central and peripheral nervous systems, play crucial roles in regulating metabolism, reproduction, and immunity, and are linked to specific behaviors like bonding and anxiety. Understanding neurobiology and accurately measuring neuropeptides is essential for addressing neurodegenerative diseases such as Alzheimer’s and Parkinson’s.
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
法规信息
新产品
此项目有
Willem J van den Brink et al.
British journal of pharmacology, 175(19), 3832-3843 (2018-07-28)
Because biological systems behave as networks, multi-biomarker approaches increasingly replace single biomarker approaches in drug development. To improve the mechanistic insights into CNS drug effects, a plasma neuroendocrine fingerprint was identified using multi-biomarker pharmacokinetic/pharmacodynamic (PK/PD) modelling. Short- and long-term D2
Willem J van den Brink et al.
The AAPS journal, 19(1), 274-285 (2016-10-28)
To reveal unknown and potentially important mechanisms of drug action, multi-biomarker discovery approaches are increasingly used. Time-course relationships between drug action and multi-biomarker profiles, however, are typically missing, while such relationships will provide increased insight in the underlying body processes.
Thiago B Kirsten et al.
Biology open, 8(5) (2019-05-01)
We have shown that exposure of rats to lipopolysaccharide (LPS) during gestation induces autistic-like behaviors in juvenile offspring and pioglitazone post treatment corrects social and communication deficits. The first objective of the present study was to evaluate the cognition of
Jorge Moreno-Fernández et al.
Nutrients, 11(10) (2019-10-09)
Iron deficiency anemia (IDA) is one of the most prevalent nutritional deficiencies worldwide. Iron plays critical roles in nervous system development and cognition. Despite the known detrimental consequences of IDA on cognition, available studies do not provide molecular mechanisms elucidating
Jen-Yin Goh et al.
Brain, behavior, and immunity, 89, 100-117 (2020-06-03)
Many psychiatric illnesses have a multifactorial etiology involving genetic and environmental risk factors that trigger persistent neurodevelopmental impairments. Several risk factors have been individually replicated in rodents, to understand disease mechanisms and evaluate novel treatments, particularly for poorly-managed negative and
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