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Merck
CN

RV1MAG-26K

MILLIPLEX® Rat Vascular Injury Panel

Configurable Rat Vascular Injury 9-Plex Panel 1

别名:

Luminex® Rat Vascular Injury Panel, Millipore Rat Vascualr Injury Panel, Rat Vascular Injury Multiplex Assay

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关于此项目

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

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产品名称

MILLIPLEX® Rat Vascular Injury Panel, Configurable Rat Vascular Injury 9-Plex Panel 1

packaging

1 ea of

assay range

accuracy: 97-108%
intra-assay cv: <10%
standard curve range: 0.1-100 ng/mL
(CINC-1/GRO/KC, IL-6, MCP-1, PAI-1 (total))
standard curve range: 0.1-15 ng/mL
(VEGF)
standard curve range: 0.1-20 ng/mL
(TNFα)
standard curve range: 0.2-150 ng/mL
(TIMP-1)
standard curve range: 0.3-200 ng/mL
(CTGF)
standard curve range: 1.4-1,000 ng/mL
(Caveolin-1)
inter-assay cv: <10%
(All other analytes)
inter-assay cv: <15%
(CINC-1/GRO/KC, PAI-1 (total), TIMP-1, TNFα)
inter-assay cv: <20%
(Caveolin-1)

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

species reactivity

rat

manufacturer/tradename

Milliplex®

Quality Level

200

Other Notes

Sensitivity: See kit protocol for individual analytes sensitivities.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 9 analytes in rat serum or plasma samples.

Analytes included: Caveolin-1, CTGF, KC/GRO (CXCL1), IL-6, MCP-1 (CCL2), PAI-1 (Total), TIMP-1, TNFα, VEGF

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:

  • Targets a broad panel of biomarkers involved in vascular injury, inflammation, and tissue remodeling
  • Includes 9 analytes covering endothelial function, chemokine signaling, cytokine activity, and angiogenesis
  • Multiplex format enables simultaneous detection from minimal sample volume
  • Compatible with rat serum, plasma, and tissue culture supernatant samples
  • Designed for vascular injury, fibrosis, inflammation, and regenerative research
Benefits:

  • Provides a detailed molecular profile of vascular damage and repair mechanisms
  • Supports evaluation of therapeutic interventions targeting vascular inflammation and remodeling
  • Facilitates monitoring of angiogenic and fibrotic responses in preclinical rat models
  • Enhances understanding of immune cell recruitment and cytokine signaling in vascular pathology
  • Streamlines experimental workflows with high-throughput, multi-analyte capability

General description

Biomarkers such as Caveolin-1, CTGF, KC/GRO (CXCL1), IL-6, MCP-1 (CCL2), PAI-1 (Total), TIMP-1, TNFα, and VEGF are central to understanding vascular injury, inflammation, and tissue remodeling in rat models. Caveolin-1 regulates endothelial function and vascular permeability, while CTGF is involved in fibrosis and extracellular matrix production. KC/GRO and MCP-1 are chemokines that mediate immune cell recruitment. IL-6 and TNFα are pro-inflammatory cytokines linked to vascular inflammation. PAI-1 and TIMP-1 regulate fibrinolysis and matrix turnover, and VEGF promotes angiogenesis. Together, these analytes provide a comprehensive profile of vascular damage, repair, and inflammatory signaling

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

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