BioTracker ATP-LW Live Cell Dye

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial

Adenosine-5′-triphosphate (ATP) plays an vital role in regulating cell movement, neurotransmission, and ion channels. Disruption of ATP homeostasis can induce diseases including ischemia, Parkinson′s disease and hypoglycaemia.Peroxynitrite (ONOO-) is a highly reactive nitrogen species with an extremely short biological half-life. ONOO- is known for its deleterious effects, causing irreversible damage to a range of biological targets such as lipids, proteins and nucleic acids. As a result, ONOO- is associated with diseases such as inflammation, cancer, atherosclerosis, ischemia-reperfusion injury and neurodegenerative diseases.BioTracker ATP-LW live cell dye is a dual probe for detection and imaging of ATP and peroxynitrite in live cells. The dye did not respond to presence of other reactive nitrogen/oxygen species such as H2O2 and HClO. However, ADP (adenosine diphosphate) and CTP (cytosine-5′-triphosphate) induced fluorescence enhancements. Note: BioTracker ATP-LW live cell dye is stable in DMSO but unstable is water and aqueous solution. Prepare the working solution and use it immediately. Spectral PropertiesFor ATP detection: Excitation: 450 nmEmission: 550 nmFor Peroxynitrite detection: Excitation: 520 nmEmission: 586 nmResearch Category:InflammationLive Cell Dye