BioTracker^™ MemBright 560 Live Cell Dye

The BioTracker^™ Membright-560 live cell dye is a “turn-on” fluorescence probe emitting in the orange to red spectrum for imaging of plasma membranes of live cells.

Probes specific for the plasma membrane are essential for demarcating cell boundaries. Membright dyes use a novel fluorogenic mechanism, operating in a self-quenched nanoparticle state. On contact and propagation within the cell membrane, fluorescence is turned on, producing a bright signal with low to no background. The Membright live cell membrane probes are compatible with two-photon imaging, superresolution microscopy, and can be used in live or fixed cells. Their robust photostability and lack of cytotoxicity make Membright probes optimal for protracted live cell imaging. The superior characteristics of these plasma membrane probes permit use in a diverse spectrum of fluorescence detection applications.

Spectral Properties
Fluorescence images obtained by λex = 560 nm and emission range of 567-750 nm.

Reference

Collot M et al. MemBright: A family of fluorescent membrane probes for advanced cellular imaging and neuroscience. Cell Chem. Biol. 2019, 26:600-614

Purity: > 98% confirmed by HPLC, HNMR, LC-MS and elemental analysis.

Red/orange fluorescent probe for efficient, selective labeling of the plasma membrane in live cells. Suitable for superresolution microscopy.

Magenta solution

Store long term at -20°C, protected from light.

Live cell fluorescent imaging, flow cytometry

BioTracker is a trademark of Merck KGaA, Darmstadt, Germany

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.