BioTracker^™ MemBright 640 Live Cell Dye

The BioTracker^™ Membright-640 live cell dye is a “turn-on” fluorescence probe emitting in the far red spectrum for the imaging of plasma membranes of live cells.

Probes specific for the plasma membrane are fundamental tools for marking cell boundaries. Membright probes use a unique mechanism, existing in a self-quenched nanoparticle state. On contact and propagation within the cell membrane, the probe becomes fluorogenic, demonstrating remarkably high signal-to-background ratio. These live cell membrane probes are compatible with two-photon imaging, superresolution imaging, and are suitable for use in live or fixed cells. Their exceptional photostability and lack of cytotoxicity make Membright probes optimal for long-term imaging studies. The key characteristics of these plasma membrane probes permit use in a broad spectrum of fluorescence microscopy applications, and in flow cytometry.

Spectral Properties
Fluorescence images obtained by λex = 640 nm and emission range of 640-800 nm.

Reference

Collot M et al. MemBright: A family of fluorescent membrane probes for advanced cellular imaging and neuroscience. Cell Chem. Biol. 2019, 26:600-614

Purity: > 98% confirmed by HPLC, HNMR, LC-MS and elemental analysis.

Far red fluorescent probe for efficient, selective labeling of the plasma membrane in live cells. Suitable for superresolution microscopy.

Blue solution

Store long term at -20°C, protected from light.

Live cell fluorescent imaging, flow cytometry

BioTracker is a trademark of Merck KGaA, Darmstadt, Germany

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.