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Merck
CN

SCYT-91K-PXBK14

MILLIPLEX® Ovine Cytokine/Chemokine Panel 1

Bulk (Space Saver) Premixed Ovine Cytokine/Chemokine 14-Plex Panel 1

别名:

ovine cytokine kit, sheep chemokine panel, sheep cytokine panel

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NACRES:
NA.47
UNSPSC Code:
12161503

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产品名称

MILLIPLEX® Ovine Cytokine/Chemokine Panel 1,

species reactivity

sheep

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

accuracy: 101
(Galectin-1), accuracy: 102
(PD-L2), accuracy: 103
(CD80/B7-1), accuracy: 103
(IFNγ), accuracy: 104
(CTLA-4/CD152), accuracy: 104
(TLR-2), accuracy: 105
(4-1BBL/TNFSF9), accuracy: 105
(BCA-1/CXCL-13), accuracy: 105
(CD25/IL-2Rα), accuracy: 105
(IL-10), accuracy: 105
(LAG-3), accuracy: 106
(5’-NT/CD73), accuracy: 106
(PD-1), accuracy: 106
(TIM-3), accuracy: 106
(TNFα), accuracy: 107
(CD137/4-1BB), accuracy: 107
(CD27), accuracy: 108
( Galectin-3), accuracy: 108
(E-Cadherin), accuracy: 108
(HVEM), accuracy: 109
(CD40), accuracy: 109
(GITR), accuracy: 110
(B7-H2/ICOSL), accuracy: 110
(CD226/DNAM-1), accuracy: 111
(BTLA), accuracy: 94
(GranzymeB), accuracy: 95
(B7-H3/CD276), accuracy: 96
(PD-L1), sensitivity: 14 - 10000  pg/mL
(4-1BBL/TNFSF9), standard curve range: 1.4 - 1000 pg/mL
(HVEM), standard curve range: 1.4 - 1000 pg/mL
(IFNγ), standard curve range: 11 - 8000  pg/mL
(IL-10), standard curve range: 137 - 100000 pg/mL
(5’-NT/CD73), standard curve range: 14 - 10000 pg/mL
(CD226/DNAM-1), standard curve range: 14 - 10000 pg/mL
(CD40), standard curve range: 14 - 10000 pg/mL
(PD-L1), standard curve range: 2.7 - 2000  pg/mL
(CD25/IL-2Rα), standard curve range: 21 - 15000 pg/mL
(BTLA), standard curve range: 27 - 20000 pg/mL
(B7-H2/ICOSL), standard curve range: 27 - 20000 pg/mL
(BCA-1/CXCL-13), standard curve range: 3.4 - 2500  ng/mL
(Galectin-1), standard curve range: 3.4 - 2500 ng/mL
(B7-H3/CD276), standard curve range: 34.3 - 25000 pg/mL
(CD80/B7-1), standard curve range: 342 - 250000 pg/mL
(E-Cadherin), standard curve range: 4.1 - 3000  pg/mL
(TNFα), standard curve range: 41 - 30000  pg/mL
(GITR), standard curve range: 41 - 30000  pg/mL
(GranzymeB), standard curve range: 41 - 30000 pg/mL
(Galectin-3), standard curve range: 412 - 300000  pg/mL
(LAG-3), standard curve range: 412 - 300000 pg/mL
(TLR-2), standard curve range: 5.5 - 4000  pg/mL
(CD137/4-1BB ), standard curve range: 5.5 - 4000  pg/mL
(CTLA-4/CD152), standard curve range: 5.5 - 4000  pg/mL
(TIM-3), standard curve range: 55 - 40000 pg/mL
(CD27), standard curve range: 55 - 40000 pg/mL
(PD-1), standard curve range: 6.9 - 5000  pg/mL
(PD-L2), inter-assay cv: <20%
intra-assay cv: <10%

technique(s)

multiplexing: suitable

input

cell culture supernatant(s)

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

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General description

Cytokines and chemokines play crucial roles in the immune response of sheep, mediating communication between immune cells and regulating various physiological processes. These signaling molecules are involved in the development and activation of immune cells, influencing both innate and adaptive immunity. Understanding the specific functions and interactions of cytokines and chemokines in sheep is essential for improving health management and disease resistance in livestock.

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 14 analytes in sheep serum, plasma, and cell culture supernatants.

Analytes included: IFNγ, IL-1α, IL-1β, IL-4, IL-6, IL-8 (CXCL8), IL-10, IL-17A, IL-36RA (IL-1F5), IP-10 (CXCL10), MIP-1α (CCL3), MIP-1β (CCL4), TNFα, VEGF-A

Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Features and Benefits

Compact Storage: Space saver format reduces packaging volume, making it easier to store multiple kits in limited lab space.

Unique Offering: The only commercially available multiplex panel for cytokine and chemokine detection in sheep.

Lot-to-Lot Consistency: Standard and QC lots are benchmarked against reference lots to ensure reproducibility across batches, critical for longitudinal studies.

Supports Cytokine Modulation Studies: Ideal for evaluating the therapeutic potential of cytokines, especially in inflammation-related disease models.

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

10 - Combustible liquids

wgk

WGK 3

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