产品名称
Anti-SMO Mouse mAb (1D9), liquid, clone 1D9, Calbiochem®
biological source
mouse
antibody form
purified antibody
antibody product type
primary antibodies
clone
1D9, monoclonal
form
liquid
does not contain
preservative
species reactivity
human
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
avoid repeated freeze/thaw cycles
dilution
(Immunoblotting (1-5 µg/mL))
isotype
IgG2a
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... SMO(6608)
Analysis Note
Positive Control
A431 cells
A431 cells
Application
Immunoblotting (1-5 g/ml)
Disclaimer
Toxicity: Regulatory Review (Z)
General description
Purified mouse monoclonal antibody. Recognizes the ~75 kDa SMO protein.
Recognizes the ~75 kDa SMO protein in A431 cells.
This Anti-SMO Mouse mAb (1D9) is validated for use in Immunoblotting for the detection of SMO.
Immunogen
Full-length, recombinant, human SMO (aa 653-787) expressed as a GST fusion protein
Other Notes
Variables associated with assay conditions will dictate the proper working dilution.
Physical form
In PBS, pH 7.2.
Preparation Note
Following initial thaw, aliquot and freeze (-20°C).
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Silvia Pietrobono et al.
Cell death & disease, 9(2), 142-142 (2018-02-06)
Aberrant activation of the Hedgehog (HH) signaling is a critical driver in tumorigenesis. The Smoothened (SMO) receptor is one of the major upstream transducers of the HH pathway and a target for the development of anticancer agents. The SMO inhibitor
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