biological source
pigeon breast
form
suspension
specific activity
~80 units/mg protein (At 25 °C with CoA and acetyl-D,L-carnitine as the substrates.)
packaging
pkg of 1 mL (5 mg)
manufacturer/tradename
Roche
technique(s)
analytical sample preparation: suitable
color
white
optimum pH
7.3-8.0
solubility
water: miscible
NCBI accession no.
UniProt accession no.
application(s)
life science and biopharma
foreign activity
Acetyl-CoA-deacylase 0.01%
storage temp.
2-8°C
Gene Information
pigeon ... CRAT(102084317)
General description
乙酰辅酶 A：肉碱乙酰基转移酶
肉碱乙酰转移酶是一种线粒体酶，对生物燃料利用至关重要。它存在于线粒体基质和过氧化物酶体中，参与脂肪酸代谢。它有利于乙酰辅酶A和肉毒碱分别转化为乙酰肉碱和辅酶A。这种转化通过输入乙酰基进行线粒体氧化来促进过氧化物酶体β-氧化。
Physical form
悬浮液，溶剂为2.9M硫酸铵溶液，含50mM磷酸钾，1mM EDTA，pH约7.5
Analysis Note
污染物：储存缓冲液的乙酰-CoA-脱酰酶离子含量＆lt; 0.01%。
Other Notes
仅用于生命科学研究。不可用于诊断。
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
No data available
flash_point_c
No data available
法规信息
低风险生物材料
动植物源性产品
此项目有
Y Elgersma et al.
The EMBO journal, 14(14), 3472-3479 (1995-07-17)
Carnitine acetyltransferase (CAT) is present in mitochondria and peroxisomes of oleate-grown Saccharomyces cerevisiae. Both proteins are encoded by the same gene, YCAT, which encodes a protein with a mitochondrial targeting signal (MTS) at the N-terminus, and a peroxisomal targeting signal
Jiankang Liu et al.
Proceedings of the National Academy of Sciences of the United States of America, 99(4), 1876-1881 (2002-02-21)
We test whether the dysfunction with age of carnitine acetyltransferase (CAT), a key mitochondrial enzyme for fuel utilization, is due to decreased binding affinity for substrate and whether this substrate, fed to old rats, restores CAT activity. The kinetics of
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