10127647001
Roche
D-葡萄糖-6-磷酸 二钠盐 水合物
mol wt (glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2), pkg of 5 g
别名:
G-6-P-Na2, 鲁氏酯
表单
solid
分子量
(glucose-6-P: Mr = 260.2, glucose-6-P-Na2: Mr = 304.2)
包装
pkg of 5 g
制造商/商品名称
Roche
运输
ambient
SMILES字符串
O.[Na+].[Na+].OC1O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H](O)[C@H]1O
InChI
1S/C6H13O9P.2Na.H2O/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;;;/h2-10H,1H2,(H2,11,12,13);;;1H2/q;2*+1;/p-2/t2-,3-,4+,5-,6?;;;/m1.../s1
InChI key
UUWJZXLTPORJKW-WYFATIGWSA-L
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一般描述
Disodium salt
应用
Substrate for glucose-6-phosphatase.
生化/生理作用
In mammals, glucose-6-phosphate (G6P) is formed by a kinase acting on glucose. It plays several roles and has its fate determined accordingly. It can get converted back to glucose by a phosphatase enzyme. It can pass into glycogen, or enter into the energy-yielding Embden-Meyerhof path or into the 6-phosphogluconate pathway. Increased levels of blood glucose result in elevated levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. This elevated intracellular level of G6P activates glycogen synthase. G6P may also be involved in the negative regulation of phosphorylation of glycogen synthase via cyclic AMP-stimulated protein kinase.
制备说明
77% glucose-6-P (enzymatic), 13% sodium, 8% water
C6H11O9PNa2
分析说明
Contaminants: <0.2% glucose (enzymatic)
其他说明
仅用于生命科学研究。不可用于诊断。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
涉药品监管产品
此项目有
THE ROLE OF GLUCOSE 6-PHOSPHATE IN THE REGULATION OF GLUCOSE METABOLISM IN HUMAN ERYTHROCYTES.
I A ROSE et al.
The Journal of biological chemistry, 239, 12-17 (1964-01-01)
C Villar-Palasí et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 11(7), 544-558 (1997-06-01)
Elevated blood glucose concentrations result in increased intracellular levels of glucose 6-phosphate in liver, skeletal muscle, and adipose tissue. In liver, blood glucose concentrations are the main factor in control of the synthesis of glycogen; insulin has only a potentiating
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