biological source
yeast
form
lyophilized
specific activity
~20 units/mg protein (At 25 °C with acetaldehyde as the substrate.)
packaging
pkg of 250 U
manufacturer/tradename
Roche
optimum pH
8.75
relevant disease(s)
cancer
storage temp.
2-8°C
General description
乙醛脱氢酶（ALDH）是一种可溶性酶，活性依赖于钾离子和半胱氨酸。ALDH家族由19个人类基因组成。ALDH基因在细胞核、胞质、线粒体和内质网中表达。ALDH是烟酰胺腺嘌呤二核苷酸磷酸（NADH）和烟酰胺腺嘌呤二核苷酸磷酸（NADPH）循环系统的组成部分。
Application
乙醛脱氢酶已用于评估光纤生物传感器，从而测定液相中的乙醛（AcH）（AcH生物传感器）。
Biochem/physiol Actions
乙醛脱氢酶（ALDH）可调节非P450乙醛还原酶系统。它可保护细胞免受有毒乙醛的影响。该基因的突变与Sjogren Larsson综合征、Larsson综合征、II型高蛋白血症和癌症相关。ALDH参与了乙醛氧化成酸的反应。ALDH-2可降低因心肌梗塞或心脏手术后出现的心脏缺血。
Physical form
用磷酸钾缓冲液（pH 值约为 6）稳定酶。
Analysis Note
污染物： 分别是 <0.01%“NADH氧化酶”、ADH 和 LDH
Other Notes
仅用于生命科学研究。不可用于诊断。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Inhalation - STOT RE 2
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
常规特殊物品
此项目有
Yeast Aldehyde Dehydrogenase II. PROPERTIES OF THE HOMOGENEOUS ENZYME PREPARATIONS
Charles R. Steinman and WILLIAM B. JAKOBY
The Journal of Biological Chemistry, 243(4), 730-734 (1965)
Improved sensitivity of acetaldehyde biosensor by detecting ADH reverse reaction-mediated NADH fluoro-quenching for wine evaluation
Iitani K, et al.
ACS sensors, 2(7), 940-946 (2017)
Kenta Iitani et al.
Sensors (Basel, Switzerland), 23(13) (2023-07-14)
The molecule 2-nonenal is renowned as the origin of unpleasant human aging-related body odor that can potentially indicate age-related metabolic changes. Most 2-nonenal measurements rely on chromatographic analytical systems, which pose challenges in terms of daily usage and the ability
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 10171832001 | 04061838668455 |