产品名称
组蛋白, from calf thymus
form
lyophilized
packaging
pkg of 10 mg
manufacturer/tradename
Roche
shipped in
wet ice
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
组蛋白在染色质的组织和修饰中发挥重要作用。核小体是染色质的基本单位。它由两个各含组蛋白H2A、H2B、H3和H4的分子组成，包裹着大约146bp的DNA。组蛋白H1在DNA入口和出口点与核小体结合并使其稳定。
Application
小牛胸腺组蛋白可用于：
- 体外激酶活性测定，检测蛋白激酶A催化的组蛋白磷酸化程度。
- 检测水稻蛋白精氨酸甲基转移酶（OsPRMT）的体外甲基转移酶活性。
- 抗组蛋白ELISA。
General description
从小牛胸腺中分离得到的组蛋白H1、H2A、H2B、H3和H4的混合物。
组蛋白是一组DNA结合蛋白，其特征是赖氨酸和精氨酸含量较高。分离和表征了五种不同的组蛋白级分。它们被命名为组蛋白H1、H2A、H2B、H3和H4。H1级分富含赖氨酸，而H2A和H2B级分略微富含赖氨酸，H3和H4级分富含精氨酸。组蛋白的分子量约为11-21 kda，取决于具体级分。
组蛋白是一组DNA结合蛋白，其特征是赖氨酸和精氨酸含量较高。分离和表征了五种不同的组蛋白级分。它们被命名为组蛋白H1、H2A、H2B、H3和H4。H1级分富含赖氨酸，而H2A和H2B级分略微富含赖氨酸，H3和H4级分富含精氨酸。组蛋白的分子量约为11-21 kda，取决于具体级分。
Other Notes
仅用于生命科学研究。不可用于诊断。
Physical form
冻干粉（天然组蛋白H1、H2A、H2B、H3和H4的混合物）。
Preparation Note
工作浓度：1-5 mg/ml。
工作溶液：推荐的溶剂是双蒸馏水。
储存条件（工作溶液）：水溶液在-15至-25 °C下可稳定保存几个月。
避免反复冻融！
工作溶液：推荐的溶剂是双蒸馏水。
储存条件（工作溶液）：水溶液在-15至-25 °C下可稳定保存几个月。
避免反复冻融！
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
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