产品名称
秋水仙胺, solution, suitable for blocking, sterile; 0.2 μm filtered
SMILES string
CN[C@H]1CCc2cc(OC)c(OC)c(OC)c2C3=CC=C(OC)C(=O)C=C13
InChI
1S/C21H25NO5/c1-22-15-8-6-12-10-18(25-3)20(26-4)21(27-5)19(12)13-7-9-17(24-2)16(23)11-14(13)15/h7,9-11,15,22H,6,8H2,1-5H3/t15-/m0/s1
InChI key
NNJPGOLRFBJNIW-HNNXBMFYSA-N
description
N-methyl-N-deacetyl-colchicine
sterility
sterile; 0.2 μm filtered
form
solution
packaging
pkg of 20 mL (10 μg/ml)
manufacturer/tradename
Roche
technique(s)
blocking: suitable
impurities
microbial, tested
solubility
water: miscible
storage temp.
2-8°C
Quality Level
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Application
秋水仙碱可抑制有丝分裂纺锤体的形成。它可用于增加染色体分析中中期细胞的百分比。
Biochem/physiol Actions
通常在核型分析和细胞周期研究中，其可在细胞周期的特定阶段增加有丝分裂细胞的产量。这可以通过多种方式来实现，其中最流行的是使用细胞周期同步剂，例如地美考辛。地美考辛会将细胞停滞于中期，同时对有丝分裂细胞或经同步的G1和S期细胞中的生化事件无明显影响。经常会用地美可辛处理白细胞以阻止中期细胞。
General description
秋水仙胺也被称为地美辛星。它的通用名称是 N-甲基-N-去乙酰秋水仙碱。秋水仙胺可解聚微管并在中期阻断有丝分裂。
Other Notes
仅用于生命科学研究。不用于诊断操作。
Physical form
溶液（10 μg/ml），已通过0.2 μm孔径滤膜过滤。
存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
does not flash
flash_point_c
does not flash
法规信息
涉药品监管产品
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