10295892001
Roche
秋水仙胺
solution, suitable for blocking, sterile; 0.2 μm filtered
别名:
地美可辛, N-去乙酰-N-甲基秋水仙碱
描述
N-methyl-N-deacetyl-colchicine
质量水平
无菌性
sterile; 0.2 μm filtered
表单
solution
包装
pkg of 20 mL (10 μg/ml)
制造商/商品名称
Roche
技术
blocking: suitable
杂质
microbial, tested
溶解性
water: miscible
储存温度
2-8°C
SMILES字符串
CN[C@H]1CCc2cc(OC)c(OC)c(OC)c2C3=CC=C(OC)C(=O)C=C13
InChI
1S/C21H25NO5/c1-22-15-8-6-12-10-18(25-3)20(26-4)21(27-5)19(12)13-7-9-17(24-2)16(23)11-14(13)15/h7,9-11,15,22H,6,8H2,1-5H3/t15-/m0/s1
InChI key
NNJPGOLRFBJNIW-HNNXBMFYSA-N
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一般描述
秋水仙胺也被称为地美辛星。它的通用名称是 N-甲基-N-去乙酰秋水仙碱。秋水仙胺可解聚微管并在中期阻断有丝分裂。
应用
秋水仙碱可抑制有丝分裂纺锤体的形成。它可用于增加染色体分析中中期细胞的百分比。
生化/生理作用
通常在核型分析和细胞周期研究中，其可在细胞周期的特定阶段增加有丝分裂细胞的产量。这可以通过多种方式来实现，其中最流行的是使用细胞周期同步剂，例如地美考辛。地美考辛会将细胞停滞于中期，同时对有丝分裂细胞或经同步的G1和S期细胞中的生化事件无明显影响。经常会用地美可辛处理白细胞以阻止中期细胞。
外形
溶液（10 μg/ml），已通过0.2 μm孔径滤膜过滤。
其他说明
仅用于生命科学研究。不用于诊断操作。
储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
does not flash
闪点(°C)
does not flash
法规信息
涉药品监管产品
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