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Merck
CN

10982962001

Roche

N-Acetyl-β-D-Glucosaminidase Standard (NAG Standard)

from beef kidney

别名:

NAG standard

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关于此项目

UNSPSC Code:
12352204
Specific activity:
~20 mU/mL
Biological source:
bovine kidney
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biological source

bovine kidney

form

lyophilized

specific activity

~20 mU/mL

packaging

pkg of 5 × 3 mL (5 x 400 μg)

manufacturer/tradename

Roche

technique(s)

activity assay: suitable

color

white to light yellow

solubility

water: soluble

application(s)

life science and biopharma

storage temp.

20-25°C

General description

Standard for the determination of NAG activity in urine research samples with the aid of the Test-Combination N-acetyl-β-D-glucosaminidase.
N-Acetyl-β-D-Glucosaminidase is a high molecular weight lysosomal enzyme existing as two isofomrs, Isoenzyme-A and Isoenzyme-B. It is present in human kidney. It has high molecular weight. It is highly active in renal proximal tubular cells. It has been reported that overexpressed urine-NAG reflects the proximal tubular dysfunction of the kidney.

Application

The NAG standard is used for the determination of NAG activity in urine in life science research applications, with the aid of N-acetyl-β-D-glucosaminidase. It can be used in automatic analyzers.

Preparation Note

Storage conditions (working solution): 2 to 8 °C
Stability of the standard solution
The solution is stable for at least 1 month stored at 2 to 8 °C, protected from light.
Preparation of the standard solution
Dissolve contents of one bottle with 3 ml double distilled water, close bottle and wait for 5 minutes. Dissolve contents completely by gentle swirling. Avoid creating foam.
Keep protected from light.

Other Notes

For life science research only. Not for use in diagnostic procedures.
Volume Activity: The activity of the NAG standard is approximately 20 mU N-acetyl-β-D-glucosaminidase from beef kidney per ml. For exact values, see data printed on the label.

hcodes

Hazard Classifications

Aquatic Chronic 3

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

does not flash

flash_point_c

does not flash

法规信息

低风险生物材料
动植物源性产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Ravi Babu Kalahasthi et al.
Journal of occupational medicine and toxicology (London, England), 2, 5-5 (2007-07-31)
The present study was carried out to determine the effect of cadmium exposure on Urinary N-acetyl-beta -D-glucosaminidase and its isoenzymes A and B in workers exposed at cadmium plating. 50 subjects using cadmium during cadmium plating formed the study group.

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