产品名称
乙酰辅酶 A, 85% (Enzymatic and Absorbance), 2% (lithium)
description
Chemical Formula: C23H35N7O17P3SLi3
assay
85% (Enzymatic and Absorbance)
form
solid
mol wt
Mr 809.6 (acetyl-CoA)
Mr 827.4 (acetyl-CoA-Li3)
packaging
pkg of 010 mg (10101893001)
pkg of 200 mg (11585371001)
pkg of 050 mg (10101907001)
manufacturer/tradename
Roche
concentration
2% (lithium)
storage temp.
2-8°C
Quality Level
Application
乙酰辅酶 A 用于使用放射性同位素测定细胞提取物中的 CAT 酶活性。细胞提取物中的 CAT 酶活性催化乙酰基从乙酰辅酶 A 转移到氯霉素。已经开发了许多测定来测量细胞提取物中的 CAT 活性。乙酰辅酶 A 也已用于测定柠檬酸合酶活性。
Biochem/physiol Actions
乙酰辅酶 A（Ac-CoA）是糖酵解的最终产物，参与 Ac-CoA 途径，这是碳化合物的代谢途径。Ac-CoA 在胆固醇合成中十分重要。它还参与脂肪酸的生物合成和多胺（如精胺和亚精胺）的分解代谢。低水平的 Ac-CoA 导致神经胶质细胞和神经元功能的丧失。酮体和甘油三酯在水解时产生 Ac-CoA，这间接导致组蛋白乙酰化增加。
General description
乙酰辅酶 A，三锂盐
Other Notes
仅用于生命科学研究。不可用于诊断。
Preparation Note
工作溶液：最佳溶剂：具有弱酸性 pH（4 至 5）的水或水溶液。
储存条件（工作溶液）：-15 至 -25°C
50mg/ml 磷酸盐缓冲液，pH 7，在 -15 至 -25℃ 下，可稳定保存 3 周。未冻存的溶液应立即使用。
储存条件（工作溶液）：-15 至 -25°C
50mg/ml 磷酸盐缓冲液，pH 7，在 -15 至 -25℃ 下，可稳定保存 3 周。未冻存的溶液应立即使用。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Biochemistry null
L Lu et al.
The Journal of biological chemistry, 271(31), 18920-18924 (1996-08-02)
Polyamine catabolism is rate limited by spermidine/spermine N1-acetyltransferase (SSAT). Although the amino acid sequence of SSAT is known, the substrate binding and catalytic sites are not. The goal of this study was to define the region responsible for acetyl coenzyme
Eileen B Ekstrom et al.
Applied and environmental microbiology, 69(9), 5414-5422 (2003-09-06)
Sulfate-reducing bacteria (SRB) in anoxic waters and sediments are the major producers of methylmercury in aquatic systems. Although a considerable amount of work has addressed the environmental factors that control methylmercury formation and the conditions that control bioavailability of inorganic
Jean-Pierre Montmayeur and Johannes le Coutre
Fat Detection-Taste, Texture, and Post Ingestive Effects null
Morten Scheibye-Knudsen et al.
Cell metabolism, 20(5), 840-855 (2014-12-03)
Cockayne syndrome (CS) is an accelerated aging disorder characterized by progressive neurodegeneration caused by mutations in genes encoding the DNA repair proteins CS group A or B (CSA or CSB). Since dietary interventions can alter neurodegenerative processes, Csb(m/m) mice were
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