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关于此项目
经验公式（希尔记法）:
C21H26N7Na4O17P3 · xH2O
化学文摘社编号:
分子量:
833.35 (anhydrous basis)
UNSPSC Code:
41106305
PubChem Substance ID:
MDL number:
NACRES:
NA.54
Assay:
97% (dry weight)
Form:
powder
Storage temp.:
2-8°C
description
Tetrasodium salt
assay
97% (dry weight)
form
powder
packaging
pkg of 1 g (10621706001), pkg of 100 mg (10107824001), pkg of 500 mg (10621692001)
manufacturer/tradename
Roche
λmax
260 and 340 nm
shipped in
wet ice
storage temp.
2-8°C
SMILES string
[Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@H]2O[C@@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@H](O)[C@@H]2O
InChI
1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11+,13-,14+,15-,16+,20-,21+;;;;/m0..../s1
InChI key
WYWWVJHQDVCHKF-MPUNMZHWSA-J
General description
- 吸光系数：在260 nm处为15.0 x 103 l x mol-1 x cm-1 ，在340 nm处为6.3 x 103 l x mol-1 x cm-1
- 最大吸收波长：260 nm和340 nm
- 分子量：NADPH-Na4: Mr = 833.4, NADPH: Mr = 745.4
- 在水中的pH值：8.0 ± 1.0 (10 mg/ml)
无定形粉末，在氮气下装瓶。
Application
NADPH-RO已被用于测定硫氧还蛋白还原酶活性。
Biochem/physiol Actions
NADPH是许多氧化还原酶(包括一氧化氮合成酶)的电子供体和辅助因子。
Preparation Note
储存条件（工作溶液）：2至8°C
浓度10 mg/ml，溶剂为碳酸氢钠缓冲液，pH 9，在2至8℃下储存4周后含有至少95％NADPH。
浓度10 mg/ml，溶剂为碳酸氢钠缓冲液，pH 9，在2至8℃下储存4周后含有至少95％NADPH。
Analysis Note
- 纯度：= 97％β-NADPH-Na4，基于干重（酶法和在340nm处的吸光度）；= 80％（在260nm处的吸光度）
- 有机溶剂：=3% (GC)
吸光系数：在260 nm处为15.0 x 103 l x mol-1 x cm-1 ，在340 nm处为6.3 x 103 l x mol-1 x cm-1
Other Notes
根据固体重量包装。
仅用于生命科学研究。不可用于诊断。
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Takashi Iyanagi et al.
Archives of biochemistry and biophysics, 528(1), 72-89 (2012-09-18)
NADPH-cytochrome P450 oxidoreductase (CYPOR) and nitric oxide synthase (NOS), two members of the diflavin oxidoreductase family, are multi-domain enzymes containing distinct FAD and FMN domains connected by a flexible hinge. FAD accepts a hydride ion from NADPH, and reduced FAD
Jonna Soerensen et al.
PloS one, 3(3), e1813-e1813 (2008-03-20)
The thioredoxin-dependent system is an essential regulator of cellular redox balance. Since oxidative stress has been linked with neurodegenerative disease, we studied the roles of thioredoxin reductases in brain using mice with nervous system (NS)-specific deletion of cytosolic (Txnrd1) and
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 10107824001 | 04061838250476 |
| 10621706001 | 04061838250551 |
| 10621692001 | 04061838673817 |