01-5610
苯胺
SAJ first grade, ≥99.0%
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关于此项目
线性分子式:
C6H5NH2
化学文摘社编号:
分子量:
93.13
EC Number:
200-539-3
UNSPSC Code:
12352106
PubChem Substance ID:
Beilstein/REAXYS Number:
605631
MDL number:
产品名称
苯胺, SAJ first grade, ≥99.0%
InChI key
PAYRUJLWNCNPSJ-UHFFFAOYSA-N
InChI
1S/C6H7N/c7-6-4-2-1-3-5-6/h1-5H,7H2
SMILES string
Nc1ccccc1
grade
SAJ first grade
vapor density
3.22 (185 °C, vs air)
vapor pressure
0.7 mmHg ( 25 °C)
assay
≥99.0%
form
liquid
autoignition temp.
1139 °F
expl. lim.
11 %
availability
available only in Japan
refractive index
n20/D 1.586 (lit.)
pH
8.8 (20 °C, 36 g/L)
bp
184 °C (lit.)
mp
−6 °C (lit.)
density
1.022 g/mL at 25 °C (lit.)
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Biochem/physiol Actions
苯胺的急性毒性涉及其在体内活化为4-羟基苯胺和与血红蛋白形成加合物。 在红细胞中，这与铁的释放和高铁血红蛋白的积累以及溶血性贫血和脾脏炎症的发展有关。长期给药时，在脾脏中常可观察到肿瘤形成。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Dam. 1 - Muta. 2 - Skin Sens. 1 - STOT RE 1
target_organs
Blood
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
158.0 °F - closed cup
flash_point_c
70 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
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The nonprotein amino acid β-aminobutyric acid (BABA) is known to protect plants against various pathogens. The mode of action is relatively diverse and specific in different plant-pathogen systems. To extend the analysis of the mode of action of BABA to
S A Vaziri et al.
Pharmacogenetics, 11(1), 7-20 (2001-02-24)
Arylamines such as 2-naphthylamine and 4-aminobiphenyl are suspected human bladder procarcinogens that require bioactivation to DNA-reactive species to exert their carcinogenic potential. The goals of the present study were (i) to assay for the presence of the arylamine acetyltransferases NAT1
M Peluso et al.
Carcinogenesis, 21(2), 183-187 (2000-02-05)
The 'Mediterranean diet', a diet rich in cereals, fruit and vegetables, has been associated with lowering the risk of a variety of cancers of the digestive tract and the bladder. In a previous study, we showed that the high phenolic
J S Bus et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 25(8), 619-626 (1987-08-01)
Aniline and several structurally-related aromatic amines produce spleen tumours in rats given high doses of compound in 2-year bioassay studies. Evaluation of the pathogenesis of the splenic lesions and characterization of the disposition of radiolabelled aniline in animals suggests that
Conghui Tang et al.
Journal of the American Chemical Society, 134(46), 18924-18927 (2012-11-08)
A novel and efficient copper-catalyzed azidation reaction of anilines via C-H activation has been developed. This method, in which the primary amine acts as a directing group by coordinating to the metal center, provides ortho azidation products regioselectively under mild
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