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Merck
CN

03-5300

丁酸

SAJ special grade, ≥99.5%

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关于此项目

线性分子式:
CH3CH2CH2COOH
化学文摘社编号:
分子量:
88.11
Beilstein:
906770
MDL编号:
UNSPSC代码:
12352106
PubChem化学物质编号:
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等级

SAJ special grade

蒸汽密度

3.04 (vs air)

蒸汽压

0.43 mmHg ( 20 °C)

方案

≥99.5%

表单

liquid

自燃温度

824 °F

expl. lim.

10 %

存货情况

available only in Japan

折射率

n20/D 1.398 (lit.)

pH值(酸碱度)

2 (25 °C, 10 g/L)
3 (20 °C, 10 g/L)

pKa (20.7 °C)

4.9

沸点

162 °C (lit.)

mp

−6-−3 °C (lit.)

密度

0.964 g/mL at 25 °C (lit.)

SMILES字符串

CCCC(O)=O

InChI

1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)

InChI key

FERIUCNNQQJTOY-UHFFFAOYSA-N

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象形图

CorrosionExclamation mark

警示用语:

Danger

危险声明

危险分类

Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B - STOT SE 3

靶器官

Respiratory system

储存分类代码

8A - Combustible corrosive hazardous materials

WGK

WGK 1

闪点(°F)

167.0 °F

闪点(°C)

75 °C

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Svenja Plöger et al.
Annals of the New York Academy of Sciences, 1258, 52-59 (2012-06-27)
Butyrate production in the large intestine and ruminant forestomach depends on bacterial butyryl-CoA/acetate-CoA transferase activity and is highest when fermentable fiber and nonstructural carbohydrates are balanced. Gastrointestinal epithelia seem to use butyrate and butyrate-induced endocrine signals to adapt proliferation, apoptosis
Ada Rephaeli et al.
International journal of cancer, 116(2), 226-235 (2005-04-01)
AN-7, a prodrug of butyric acid, induced histone hyperacetylation and differentiation and inhibited proliferation of human prostate 22Rv1 cancer cells in vitro and in vivo. In nude mice implanted with these cells, 50 mg/kg AN-7 given orally thrice a week
Hans G Cruz et al.
Nature neuroscience, 7(2), 153-159 (2004-01-28)
The rewarding effect of drugs of abuse is mediated by activation of the mesolimbic dopamine system, which is inhibited by putative anti-craving compounds. Interestingly, different GABA(B) receptor agonists can exert similarly opposing effects on the reward pathway, but the cellular
Carlo F M Welters et al.
Diseases of the colon and rectum, 45(5), 621-627 (2002-05-11)
Inflammation is a constant finding in the ileal reservoir of patients with an ileal pouch-anal anastomosis and is associated with decreased fecal concentrations of the short chain fatty acid butyrate, increased fecal pH, changes in fecal flora, and increased concentrations
Shomik Sengupta et al.
Journal of gastroenterology and hepatology, 21(1 Pt 2), 209-218 (2006-02-08)
Butyrate, the four-carbon fatty acid, is formed in the human colon by bacterial fermentation of carbohydrates (including dietary fiber), and putatively suppresses colorectal cancer (CRC). Butyrate has diverse and apparently paradoxical effects on cellular proliferation, apoptosis and differentiation that may

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