21-1430
烟酸
SAJ special grade, ≥99.5%
别名:
3-吡啶甲酸, 吡啶-3-羧酸, 尼亚生, 抗糙皮病因子, 维生素 B3
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关于此项目
经验公式（希尔记法）:
C6H5NO2
化学文摘社编号:
分子量:
123.11
EC Number:
200-441-0
UNSPSC Code:
12352005
PubChem Substance ID:
Beilstein/REAXYS Number:
109591
MDL number:
InChI key
PVNIIMVLHYAWGP-UHFFFAOYSA-N
InChI
1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
SMILES string
OC(=O)c1cccnc1
grade
SAJ special grade
assay
≥99.5%
form
powder
availability
available only in Japan
color
white
mp
236-239 °C (lit.)
solubility
ethanol: 12.5 g/L at 25 °C, water: soluble 180 g/L at 20 °C
density
1.473 g/cm3 at 25 °C
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 1
flash_point_f
379.4 °F - closed cup
flash_point_c
193 °C - closed cup
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
John R Guyton et al.
Journal of the American College of Cardiology, 62(17), 1580-1584 (2013-08-07)
This study sought to examine the relationship between niacin treatment, lipoproteins, and cardiovascular (CV) outcomes in this secondary analysis of the AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes) trial. During a
Koon K Teo et al.
Stroke, 44(10), 2688-2693 (2013-07-25)
In Atherothrombosis Intervention in Metabolic Syndrome with low HDL/High Triglycerides: Impact on Global Health Outcomes (AIM-HIGH) trial, addition of extended-release niacin (ERN) to simvastatin in participants with established cardiovascular disease, low high-density lipoprotein cholesterol, and high triglycerides had no incremental
Martina Lukasova et al.
Trends in pharmacological sciences, 32(12), 700-707 (2011-09-29)
Nicotinic acid (niacin) has been used for decades to prevent and treat atherosclerosis. The well-documented antiatherogenic activity is believed to result from its antidyslipidemic effects, which are accompanied by unwanted effects, especially a flush. There has been renewed interest in
E T Bodor et al.
British journal of pharmacology, 153 Suppl 1, S68-S75 (2007-11-27)
Nicotinic acid has been used for decades to treat dyslipidaemic states. In particular its ability to raise the plasma HDL cholesterol concentration has led to an increased interest in its pharmacological potential. The clinical use of nicotinic acid is somewhat
Amandine Girousse et al.
PLoS biology, 11(2), e1001485-e1001485 (2013-02-23)
When energy is needed, white adipose tissue (WAT) provides fatty acids (FAs) for use in peripheral tissues via stimulation of fat cell lipolysis. FAs have been postulated to play a critical role in the development of obesity-induced insulin resistance, a
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