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Merck
CN

00180585

金丝桃甙

primary reference standard

别名:

槲皮素 3-D-半乳糖苷, 3,3′,4′,5,7-五羟基黄酮 3-D-半乳糖苷, 海棠因, 金丝桃苷

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关于此项目

经验公式(希尔记法):
C21H20O12
化学文摘社编号:
分子量:
464.38
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
207-580-6
Beilstein/REAXYS Number:
5784795
MDL number:
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InChI

1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15+,17+,18-,21+/m1/s1

SMILES string

OC[C@H]1O[C@@H](OC2=C(Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@H]1O

InChI key

OVSQVDMCBVZWGM-DTGCRPNFSA-N

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

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General description

由HWI pharma services GmbH生产并鉴定。
通过定量NMR测得的准确含量可参见证书。
金丝桃苷是一种黄酮醇苷化合物,用于中药,具有多种有益作用,如抗炎、抗氧化、抗病毒和抗癌。

Application

主要参考标准可用于鉴定、分析和纯度测试、方法开发和验证。

他还可被用于以下:

  • 可发高效液相色谱-质谱法测定大鼠血浆样品经蛋白质沉淀和液-液萃取处理后的金丝桃苷
  • 通过HPLC结合二极管阵列检测(DAD)对用于中药的 罗布麻 刺五加 植物样品中的金丝桃苷、异槲皮苷和刺五加苷 E进行多残留分析
  • S天山花楸 叶样品中用离子液体真空微波辅助提取(ILVMAE)芦丁、金丝桃苷和橙皮苷,并随后用HPLC定量
  • 使用高效液相色谱结合分光光度检测(HPLC-UV)同时检测和定量山楂花和叶提取物样品中的牡荆素、芦丁、金丝桃苷和槲皮素

Biochem/physiol Actions

通过清除活性氧物质和增强抗氧化酶,特别是过氧化氢酶和谷胱甘肽过氧化物酶的活性,防止过氧化物诱导的细胞氧化损伤。

Other Notes

这种化合物常见于以下属的植物中:山楂、桉树、金丝桃、接骨木
黄酮醇糖苷广泛分布于植物中,包括含羞草和圣约翰草。

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

No data available

flash_point_c

No data available


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mao-Hua Ping
Cancer management and research, 12, 11773-11782 (2020-11-26)
Hyperin is an effective monomer extracted from Malvaceae plant Abelmoschus, which is a flavonol glycoside compound. Hyperin performs a variety of pharmacological activities, such as analgesia, antioxidation, anti-inflammation, avoiding microthrombosis, regulating immune function, inhibiting tumor cell growth. But the role
Joshua M Hicks et al.
Journal of AOAC International, 95(5), 1406-1411 (2012-11-28)
A single-laboratory-validated NMR spectroscopy method was established for determining the quantity of chlorogenic acid and hyperoside from crude extract material of blueberry leaves of the species Vaccinium angustifolium var. laevifolium House. The calibration curve of chlorogenic acid showed a highly
Zi-lin Li et al.
Free radical biology & medicine, 57, 132-140 (2013-01-08)
One of the leading causes of death in the world is ischemia/reperfusion (I/R)-mediated acute myocardial infarction. There are a lot of Chinese traditional patent medicines, such as Xin'an capsules, Xin Xuening tablets, and so on, which have protective effects against
Zi-lin Li et al.
Journal of ethnopharmacology, 139(2), 388-394 (2011-11-29)
Hyperoside (Hyp) is a flavonoid compound isolated from Rhododendron ponticum L. leaves that elicits vascular protective effects in vitro. Treatment with Hyp has been found to attenuate endothelial cell damage induced by oxidative stress, but its mechanisms of action remain
Rui-Li Liu et al.
Brain research, 1469, 164-173 (2012-07-10)
Hyperoside is a flavonoid compound and widely used in clinic to relieve pain and improve cardiovascular functions. However, the effects of hyperoside on ischemic neurons and the molecular mechanisms remain unclear. Here, we used an in vitro ischemic model of

实验方案

HPTLC fingerprinting enables rapid identification of passion flower with related reference materials.

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