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Merck
CN

00190585

金丝桃素

primary reference standard

别名:

4,5,7,4′,5′,7′-六羟基-2,2′-二甲基萘并二蒽酮

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关于此项目

经验公式(希尔记法):
C30H16O8
CAS Number:
分子量:
504.44
Beilstein:
1917913
EC 号:
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24
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等级

primary reference standard

保质期

limited shelf life, expiry date on the label

制造商/商品名称

HWI

储存温度

−20°C

SMILES字符串

Cc1cc(O)c2C(=O)c3c(O)cc(O)c4c5c(O)cc(O)c6C(=O)c7c(O)cc(C)c8c1c2c(c34)c(c78)c56

InChI

1S/C30H16O8/c1-7-3-9(31)19-23-15(7)16-8(2)4-10(32)20-24(16)28-26-18(12(34)6-14(36)22(26)30(20)38)17-11(33)5-13(35)21(29(19)37)25(17)27(23)28/h3-6,31-36H,1-2H3

InChI key

BTXNYTINYBABQR-UHFFFAOYSA-N

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一般描述

Produced by HWI Analytik
Exact content can be found on the certificate

应用

草药产品分析的标准品。
It was used as reference standard in determining hypericins in St. John′s Wort using HPLC method.

其他说明

This compound is commonly found in plants of the genus: hypericum

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Theodossis A Theodossiou et al.
Molecular pharmaceutics, 6(6), 1775-1789 (2009-09-11)
Photodynamic therapy (PDT) is an established anticancer treatment employing a phototoxin (photosensitizer), visible light and oxygen. The latter is photochemically converted into reactive oxygen species, which are highly toxic to the cells. Hypericin, a natural pigment of hypericum plants, is
Pavol Miskovsky
Current drug targets, 3(1), 55-84 (2002-03-20)
Hypericin, a naturally occurring pigment, is found in certain species of plants from the genus Hypericum, the most common of which is Saint John's Wort (Hypericum perforatum). Recent interest in hypericin is provoked by the discovery that it possesses extremely
J B Hudson et al.
Antiviral research, 15(2), 101-112 (1991-02-01)
Hypericin, a photodynamic plant quinone, readily inactivated murine cytomegalovirus (MCMV), Sindbis virus, and human immunodeficiency virus type 1 (HIV-1), especially on exposure to fluorescent light. Sindbis virus was significantly more sensitive than MCMV. The inactivated MCMV, when used to infect
D E Gray et al.
Journal of AOAC International, 83(4), 944-949 (2000-09-20)
Hypericin and hyperforin are believed to be among the active constituents in common St. John's wort (Hypericum perforatum L.). Presently, dietary supplements are generally standardized to contain specified levels of hypericin and hyperforin, and the related compounds, pseudohypericin and adhyperforin.
Binghu Jiang et al.
Theranostics, 3(9), 667-676 (2013-09-21)
Hypericin has been widely studied as a potent photosensitizer for photodynamic therapy in both preclinical and clinical settings. Recently, hypericin has also been discovered to have a specific avidity for necrotic tissue. This affinity is also observed in a series

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