00344
5-氯-2-甲基-4-异噻唑啉-3-酮 溶液
~1.2% in H2O
别名:
5-氯-2-甲基-3(2H)-异噻唑酮
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关于此项目
经验公式（希尔记法）:
C4H4ClNOS
化学文摘社编号:
分子量:
149.60
Beilstein:
1210149
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
浓度
~1.2% in H2O
杂质
~0.3% 2-methyl-4-isothiazolin-3-one
~1% magnesium chloride
~25% magnesium nitrate
折射率
n20/D 1.378
mp
200-230 °C
SMILES字符串
CN1SC(Cl)=CC1=O
InChI
1S/C4H4ClNOS/c1-6-4(7)2-3(5)8-6/h2H,1H3
InChI key
DHNRXBZYEKSXIM-UHFFFAOYSA-N
警示用语：
Danger
危险声明
危险分类
Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1
储存分类代码
8B - Non-combustible corrosive hazardous materials
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
新产品
此项目有
Britta Wareing et al.
ALTEX, 37(4), 639-651 (2020-06-11)
While the skin sensitization hazard of substances can be identified using non-animal methods, the classification of potency into UN GHS sub-categories 1A and 1B remains challenging. The kinetic direct peptide reactivity assay (kDPRA) is a modification of the DPRA wherein
Sang S Lee et al.
The Journal of dermatology, 39(8), 677-681 (2012-05-03)
As many new cosmetic products are introduced into the market, attention must be given to contact dermatitis, which is commonly caused by cosmetics. We investigate the prevalence of preservative allergy in 584 patients with suspected cosmetic contact dermatitis at 11
Michael D Lundov et al.
Contact dermatitis, 63(3), 164-167 (2010-08-10)
Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) has been one of the most frequent sensitizers since the 1980s. In 2005, the use of MI alone was approved for the preservation of cosmetic and household products in the EU. Before that, MI was used in industrial
Eleanor Higgins et al.
Dermatitis : contact, atopic, occupational, drug, 24(2), 73-76 (2013-03-12)
The isothiazolinones methylchloroisothiazolinone and methylisothiazolinone (MCI/MI) are the active ingredients in a frequently used preservative in cosmetic, household, and industrial products. This study reviewed our department's cases of allergic contact dermatitis caused by MCI/MI, outlining their clinical presentation and possible
Magnus Bruze et al.
Contact dermatitis, 69(5), 263-270 (2013-10-15)
Methylisothiazolinone (MI) is used as a preservative in occupational and household products, and cosmetics. It is a part of the preparation of methylchloroisothiazolinone (MCI)/MI, which is patch tested in water in the European baseline series. However, this preparation fails to
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