01700
丙烯酰胺
purum, ≥98.0% (GC)
别名:
2-丙烯酰胺, 丙烯酸酰胺
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关于此项目
线性分子式:
CH2=CHCONH2
化学文摘社编号:
分子量:
71.08
NACRES:
NB.22
PubChem Substance ID:
eCl@ss:
39031205
UNSPSC Code:
41105319
EC Number:
201-173-7
MDL number:
Beilstein/REAXYS Number:
605349
InChI key
HRPVXLWXLXDGHG-UHFFFAOYSA-N
InChI
1S/C3H5NO/c1-2-3(4)5/h2H,1H2,(H2,4,5)
SMILES string
NC(=O)C=C
vapor density
2.45 (vs air)
vapor pressure
0.03 mmHg ( 40 °C)
grade
purum
assay
≥98.0% (GC)
bp
125 °C/25 mmHg (lit.)
mp
81-87 °C, 82-86 °C (lit.)
solubility
water: soluble 200 g/L at 20 °C
storage temp.
room temp
Quality Level
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Application
丙烯酰胺已用于制备平板凝胶梯度用于聚丙烯酰胺凝胶电泳（PAGE）。
Biochem/physiol Actions
丙烯酰胺是一种反应性水溶性乙烯基单体。它导致每个细胞神经炎的数量减少，并降低蛋白质合成的速率。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Oral
target_organs
Peripheral nervous system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
280.4 °F - closed cup
flash_point_c
138 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
M W Cunningham et al.
The Journal of experimental medicine, 164(4), 998-1012 (1986-10-01)
mAbs produced by immunization of BALB/c mice with Streptococcus pyogenes M type 5 membranes were further characterized for their reaction with S. pyogenes pep M5 protein and with autoantigens associated with human cell lines. mAbs 36.2.2 and 54.2.8 simultaneously reacted
M Nordin-Andersson et al.
Cell biology and toxicology, 19(1), 43-51 (2003-03-29)
Basal cytotoxicity, morphological changes and alterations in cell physiological and neurochemical functions were studied in differentiated human neuroblastoma (SH-SY5Y) cells during exposure to acrylamide and during a subsequent recovery period after cessation of exposure. Acrylamide induced a 20% reduction in
Arianna Rath et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(39), 15668-15673 (2013-09-11)
SDS/PAGE is universally used in biochemistry, cell biology, and immunology to resolve minute protein amounts readily from tissue and cell extracts. Although molecular weights of water-soluble proteins are reliably determined from their SDS/PAGE mobility, most helical membrane proteins, which comprise
Chun-Hua Lu et al.
Nano letters, 13(3), 1298-1302 (2013-02-21)
Copolymer chains consisting of acrylamide units and guanine (G)-containing oligonucleotide-tethered acrylamide units undergo, in the presence of K(+) ions, cross-linking by G-quadruplexes to yield a hydrogel. The hydrogel is dissociated upon addition of 18-crown-6 ether that traps the K(+) ions.
Jonas S Laursen et al.
Journal of the American Chemical Society, 135(7), 2835-2844 (2013-01-25)
Non-natural peptide analogs have significant potential for the development of new materials and pharmacologically active ligands. One such architecture, the β-peptoids (N-alkyl-β-alanines), has found use in a variety of biologically active compounds but has been sparsely studied with respect to
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