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Merck
CN

01700

Sigma-Aldrich

丙烯酰胺

purum, ≥98.0% (GC)

别名:

2-丙烯酰胺, 丙烯酸酰胺

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关于此项目

线性分子式:
CH2=CHCONH2
化学文摘社编号:
分子量:
71.08
Beilstein:
605349
EC 号:
MDL编号:
UNSPSC代码:
41105319
eCl@ss:
39031205
PubChem化学物质编号:
NACRES:
NB.22
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蒸汽密度

2.45 (vs air)

质量水平

蒸汽压

0.03 mmHg ( 40 °C)

等级

purum

方案

≥98.0% (GC)

沸点

125 °C/25 mmHg (lit.)

mp

81-87 °C
82-86 °C (lit.)

溶解性

water: soluble 200 g/L at 20 °C

储存温度

room temp

SMILES字符串

NC(=O)C=C

InChI

1S/C3H5NO/c1-2-3(4)5/h2H,1H2,(H2,4,5)

InChI key

HRPVXLWXLXDGHG-UHFFFAOYSA-N

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应用

丙烯酰胺已用于制备平板凝胶梯度用于聚丙烯酰胺凝胶电泳(PAGE)。

生化/生理作用

丙烯酰胺是一种反应性水溶性乙烯基单体。它导致每个细胞神经炎的数量减少,并降低蛋白质合成的速率。

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Oral

靶器官

Peripheral nervous system

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

280.4 °F - closed cup

闪点(°C)

138 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M W Cunningham et al.
The Journal of experimental medicine, 164(4), 998-1012 (1986-10-01)
mAbs produced by immunization of BALB/c mice with Streptococcus pyogenes M type 5 membranes were further characterized for their reaction with S. pyogenes pep M5 protein and with autoantigens associated with human cell lines. mAbs 36.2.2 and 54.2.8 simultaneously reacted
M Nordin-Andersson et al.
Cell biology and toxicology, 19(1), 43-51 (2003-03-29)
Basal cytotoxicity, morphological changes and alterations in cell physiological and neurochemical functions were studied in differentiated human neuroblastoma (SH-SY5Y) cells during exposure to acrylamide and during a subsequent recovery period after cessation of exposure. Acrylamide induced a 20% reduction in
Jonas S Laursen et al.
Journal of the American Chemical Society, 135(7), 2835-2844 (2013-01-25)
Non-natural peptide analogs have significant potential for the development of new materials and pharmacologically active ligands. One such architecture, the β-peptoids (N-alkyl-β-alanines), has found use in a variety of biologically active compounds but has been sparsely studied with respect to
Arianna Rath et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(39), 15668-15673 (2013-09-11)
SDS/PAGE is universally used in biochemistry, cell biology, and immunology to resolve minute protein amounts readily from tissue and cell extracts. Although molecular weights of water-soluble proteins are reliably determined from their SDS/PAGE mobility, most helical membrane proteins, which comprise
Janneke G F Hogervorst et al.
Critical reviews in toxicology, 40(6), 485-512 (2010-02-23)
Since 2002, it is known that the probable human carcinogen acrylamide is present in commonly consumed carbohydrate-rich foods, such as French fries and potato chips. In this review, the authors discuss the body of evidence on acrylamide carcinogenicity from both

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