01700
丙烯酰胺
purum, ≥98.0% (GC)
别名:
2-丙烯酰胺, 丙烯酸酰胺
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关于此项目
线性分子式:
CH2=CHCONH2
化学文摘社编号:
分子量:
71.08
NACRES:
NB.22
PubChem Substance ID:
eCl@ss:
39031205
UNSPSC Code:
41105319
EC Number:
201-173-7
MDL number:
Beilstein/REAXYS Number:
605349
产品名称
丙烯酰胺, purum, ≥98.0% (GC)
InChI key
HRPVXLWXLXDGHG-UHFFFAOYSA-N
InChI
1S/C3H5NO/c1-2-3(4)5/h2H,1H2,(H2,4,5)
SMILES string
NC(=O)C=C
vapor density
2.45 (vs air)
vapor pressure
0.03 mmHg ( 40 °C)
grade
purum
assay
≥98.0% (GC)
bp
125 °C/25 mmHg (lit.)
mp
81-87 °C
82-86 °C (lit.)
solubility
water: soluble 200 g/L at 20 °C
storage temp.
room temp
Quality Level
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Application
丙烯酰胺已用于制备平板凝胶梯度用于聚丙烯酰胺凝胶电泳（PAGE）。
Biochem/physiol Actions
丙烯酰胺是一种反应性水溶性乙烯基单体。它导致每个细胞神经炎的数量减少，并降低蛋白质合成的速率。
signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1 Oral
target_organs
Peripheral nervous system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
280.4 °F - closed cup
flash_point_c
138 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
M W Cunningham et al.
The Journal of experimental medicine, 164(4), 998-1012 (1986-10-01)
mAbs produced by immunization of BALB/c mice with Streptococcus pyogenes M type 5 membranes were further characterized for their reaction with S. pyogenes pep M5 protein and with autoantigens associated with human cell lines. mAbs 36.2.2 and 54.2.8 simultaneously reacted
M Nordin-Andersson et al.
Cell biology and toxicology, 19(1), 43-51 (2003-03-29)
Basal cytotoxicity, morphological changes and alterations in cell physiological and neurochemical functions were studied in differentiated human neuroblastoma (SH-SY5Y) cells during exposure to acrylamide and during a subsequent recovery period after cessation of exposure. Acrylamide induced a 20% reduction in
Jonas S Laursen et al.
Journal of the American Chemical Society, 135(7), 2835-2844 (2013-01-25)
Non-natural peptide analogs have significant potential for the development of new materials and pharmacologically active ligands. One such architecture, the β-peptoids (N-alkyl-β-alanines), has found use in a variety of biologically active compounds but has been sparsely studied with respect to
Arianna Rath et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(39), 15668-15673 (2013-09-11)
SDS/PAGE is universally used in biochemistry, cell biology, and immunology to resolve minute protein amounts readily from tissue and cell extracts. Although molecular weights of water-soluble proteins are reliably determined from their SDS/PAGE mobility, most helical membrane proteins, which comprise
Janneke G F Hogervorst et al.
Critical reviews in toxicology, 40(6), 485-512 (2010-02-23)
Since 2002, it is known that the probable human carcinogen acrylamide is present in commonly consumed carbohydrate-rich foods, such as French fries and potato chips. In this review, the authors discuss the body of evidence on acrylamide carcinogenicity from both
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